Abstract
In addition to complex natural biofilms, colonies of different yeast species represent multicellular communities that possess a specific internal organization. Cells within colonies are able to differentiate to specialized cell types that perform specific functions at specific positions. Primitive cell-tissues are thus created, the formation of which is dependent on cell–cell interactions and the transmission of signals within the colony. In addition, colonies can behave as independent multicellular entities, producing signals that enable them to mutually synchronize their development when it occurs within the same territory. As a consequence, colonies synchronously adapt to changing environments and they gain a greater capacity to exploit remnant nutrients. In this review, we summarize the current knowledge concerning cell specialization and signaling within different kinds of yeast colonies and the known aspects of communication among individual colonies.
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Anderson JM, Soll DR (1987) Unique phenotype of opaque cells in the white-opaque transition of Candida albicans. J Bacteriol 169:5579–5588
Cap M, Vachova L, Palkova Z (2009) Yeast colony survival depends on metabolic adaptation and cell differentiation rather than on stress defense. J Biol Chem 284:32572–32581
Chen H, Fink GR (2006) Feedback control of morphogenesis in fungi by aromatic alcohols. Genes Dev 20:1150–1161
Dickinson JR (1996) ‘Fusel’ alcohols induce hyphal-like extensions and pseudohyphal formation in yeasts. Microbiology 142:1391–1397
Gori K, Mortensen HD, Arneborg N, Jespersen L (2007) Ammonia production and its possible role as a mediator of communication for Debaryomyces hansenii and other cheese-relevant yeast species. J Dairy Sci 90:5032–5041
Granek JA, Magwene PM (2010) Environmental and genetic determinants of colony morphology in yeast. PLoS Genet 6:e1000823
Hall RA, De Sordi L, Maccallum DM, Topal H, Eaton R, Bloor JW, Robinson GK, Levin LR, Buck J, Wang Y, Gow NA, Steegborn C, Muhlschlegel FA (2010) CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans. PLoS Pathog 6:e1001193
Hnisz D, Schwarzmuller T, Kuchler K (2009) Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans. Mol Microbiol 74:1–15
Huang G, Srikantha T, Sahni N, Yi S, Soll DR (2009) CO(2) regulates white-to-opaque switching in Candida albicans. Curr Biol 19:330–334
Huang G, Yi S, Sahni N, Daniels KJ, Srikantha T, Soll DR (2010) N-acetylglucosamine induces white to opaque switching, a mating prerequisite in Candida albicans. PLoS Pathog 6:e1000806
Kruppa M (2009) Quorum sensing and Candida albicans. Mycoses 52:1–10
Kuthan M, Devaux F, Janderova B, Slaninova I, Jacq C, Palkova Z (2003) Domestication of wild Saccharomyces cerevisiae is accompanied by changes in gene expression and colony morphology. Mol Microbiol 47:745–754
Lachke SA, Lockhart SR, Daniels KJ, Soll DR (2003) Skin facilitates Candida albicans mating. Infect Immun 71:4970–4976
Leadsham JE, Miller K, Ayscough KR, Colombo S, Martegani E, Sudbery P, Gourlay CW (2009) Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast. J Cell Sci 122:706–715
Lindegren CC, Hamilton E (1944) Autolysis and sporulation in the yeast colony. Bot Gaz 105:316–321
Meunier JR, Choder M (1999) Saccharomyces cerevisiae colony growth and ageing: biphasic growth accompanied by changes in gene expression. Yeast 15:1159–1169
Minarikova L, Kuthan M, Ricicova M, Forstova J, Palkova Z (2001) Differentiated gene expression in cells within yeast colonies. Exp Cell Res 271:296–304
Palkova Z, Forstova J (2000) Yeast colonies synchronise their growth and development. J Cell Sci 113:1923–1928
Palkova Z, Vachova L (2003) Ammonia signaling in yeast colony formation. Int Rev Cytol 225:229–272
Palkova Z, Janderova B, Gabriel J, Zikanova B, Pospisek M, Forstova J (1997) Ammonia mediates communication between yeast colonies. Nature 390:532–536
Palkova Z, Devaux F, Ricicova M, Minarikova L, Le Crom S, Jacq C (2002) Ammonia pulses and metabolic oscillations guide yeast colony development. Mol Biol Cell 13:3901–3914
Piccirillo S, Honigberg SM (2010) Sporulation patterning and invasive growth in wild and domesticated yeast colonies. Res Microbiol 161:390–398
Piccirillo S, White MG, Murphy JC, Law DJ, Honigberg SM (2010) The Rim101p/PacC pathway and alkaline pH regulate pattern formation in yeast colonies. Genetics 184:707–716
Pisova M (1934) Anatomy of yeast colonies. Rozpravy II Tridy Ceske Akad 154:1–13 (in Czech)
Reynolds TB, Jansen A, Peng X, Fink GR (2008) Mat formation in Saccharomyces cerevisiae requires nutrient and pH gradients. Eukaryot Cell 7:122–130
Robertson LS, Fink GR (1998) The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proc Natl Acad Sci USA 95:13783–13787
Scherz R, Shinder V, Engelberg D (2001) Anatomical analysis of Saccharomyces cerevisiae stalk-like structures reveals spatial organization and cell specialization. J Bacteriol 183:5402–5413
Slutsky B, Buffo J, Soll DR (1985) High-frequency switching of colony morphology in Candida albicans. Science 230:666–669
Slutsky B, Staebell M, Anderson J, Risen L, Pfaller M, Soll DR (1987) “White-opaque transition”: a second high-frequency switching system in Candida albicans. J Bacteriol 169:189–197
Soll DR (2004) Mating-type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans. Bioessays 26:10–20
Stovicek V, Vachova L, Kuthan M, Palkova Z (2010) General factors important for the formation of structured biofilm-like yeast colonies. Fungal Genet Biol 47:1012–1022
Suzuki T, Miyamae Y, Ishida I (1991) Variation of colony morphology and chromosomal rearrangement in Candida tropicalis pK233. J Gen Microbiol 137:161–167
Vachova L, Palkova Z (2005) Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia. J Cell Biol 169:711–717
Vachova L, Devaux F, Kucerova H, Ricicova M, Jacq C, Palkova Z (2004) Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies. J Biol Chem 279:37973–37981
Vachova L, Chernyavskiy O, Strachotova D, Bianchini P, Burdikova Z, Fercikova I, Kubinova L, Palkova Z (2009a) Architecture of developing multicellular yeast colony: spatio-temporal expression of Ato1p ammonium exporter. Environ Microbiol 11:1866–1877
Vachova L, Kucerova H, Devaux F, Ulehlova M, Palkova Z (2009b) Metabolic diversification of cells during the development of yeast colonies. Environ Microbiol 11:494–504
Vachova L, Stovicek V, Hlavacek O, Chernyavskiy O, Stepanek L, Kubinova L, Palkova Z (2011) Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies. J Cell Biol 194:679–687
Vopalenska I, Stovicek V, Janderova B, Vachova L, Palkova Z (2010) Role of distinct dimorphic transitions in territory colonizing and formation of yeast colony architecture. Environ Microbiol 12:264–277
Zordan RE, Miller MG, Galgoczy DJ, Tuch BB, Johnson AD (2007) Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans. PLoS Biol 5:e256
Acknowledgements
The work was supported by grants from the Grant Agency of the Czech Republic 204/08/0718 and from the Ministry of Education LC531, Research Concepts MSM0021620858 and AV0Z50200510.
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Palková, Z., Váchová, L. (2012). Communication and Differentiation in the Development of Yeast Colonies. In: Witzany, G. (eds) Biocommunication of Fungi. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4264-2_9
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