Biocompatibility and Inertness of Gold Nanocrystallites
Some types of nanoparticles are likely considered to be inert and biocompatible, such as iron oxide, ceria, and gold nanoparticles. However, the best studied and the most commonly used nanoparticles are the gold nanoparticles also known as “colloidal gold” that is being used in biomedicine for centuries. In this chapter, I will discuss about the inert nature of gold nanoparticles and the many possible explanations to justify the same. Next, our recent work on the microbial-based S. oneidensis mediated biosynthesis followed by physical characterizations of gold nanoparticles will be presented . Finally, as an example, the inert and biocompatible nature of the biosynthesized gold nanoparticles assessed using various Gram-negative and Gram-positive bacterial cell systems will be discussed.
KeywordsBacteria Biocompatibility Gold nanoparticles Inert