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Stability and Activity of Enzymes in Ionic Liquids

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Green Solvents II

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Abstract

This chapter discusses the potential usefulness of ionic liquids with respect to biocatalysis by illustrating the stability and activity of enzymes in ionic liquids in the presence or absence of water. Ionic liquids are a class of coulombic fluids composed of organic cations like alkyl-substituted imidazolium, pyrrolidinium, and tetraalkylammonium ions and anions such as halides, tetrafluoroborates, hexafluorophosphates, tosylates, etc. The possibility of tunable solvent properties by alternation of cations and anions has made ionic liquids attractive to study biocatalysis which warrants an understanding of enzyme stability and activity in ionic liquids. This chapter systematically outlines the recent studies on the stability of enzymes and their reactivity toward a wide range of catalytic reactions. A careful approach has been taken toward analysis of relationship between stability/activity of enzymes versus chaotropic/kosmotropic nature of cations and anions of ionic liquids.

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Authors and Affiliations

  1. iCeMS Lab, Institute for Integrated Cell-Material Sciences (iCeMS), Funai Center, Kyoto University Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan

    Nusrat J. M. Sanghamitra & Takafumi Ueno

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Correspondence to Nusrat J. M. Sanghamitra .

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  1. Faculty of Engineering & Technology, Department of Applied Chemistry, Aligarh Muslim University, Aligarh, 202 002, India

    Ali Mohammad

  2. Faculty of Engineering & Technology, Department of Applied Chemistry, Aligarh Muslim University, Aligarh, 202 002, India

    Dr. Inamuddin

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© 2012 Springer Science+Business Media Dordrecht

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Sanghamitra, N.J.M., Ueno, T. (2012). Stability and Activity of Enzymes in Ionic Liquids. In: Mohammad, A., Inamuddin, D. (eds) Green Solvents II. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2891-2_10

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