Abstract
Cyclic variations in calcium (Ca2+) concentrations, through a process called excitation-contraction coupling, allow regulation of vascular smooth muscle cells contractility and thus modulation of vascular tone and blood pressure. As a second messenger, Ca2+ also activates signaling cascades leading to transcription factors activation in a process called excitation-transcription coupling. Furthermore, recent evidences indicate an interaction between post-transcriptional regulation by microRNAs (miRNAs) and Ca2+ signaling. All these actors, which are frequently altered in vascular diseases, will be reviewed here.
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Marchand, A., Abi-Gerges, A., Saliba, Y., Merlet, E., Lompré, AM. (2012). Calcium Signaling in Vascular Smooth Muscle Cells: From Physiology to Pathology. In: Islam, M. (eds) Calcium Signaling. Advances in Experimental Medicine and Biology, vol 740. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2888-2_35
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