Metastatic Spine Disease: Indications, Timing, and Outcomes for Surgery and Radiation Therapy

  • Michael A. Nikolakis
  • Charles G. FisherEmail author
Part of the Tumors of the Central Nervous System book series (TCNS, volume 6)


Metastatic spine disease is the most common neoplastic process to affect the human spine. If left untreated, the prognosis of this disease is poor, with pain and progressive loss of neurological function resulting from disease progression. The goals of treatment for spinal metastases include alleviation of pain, control of local tumor burden, stabilization or reversal of neurological dysfunction and even cure of the neoplastic process. Surgery, radiotherapy and radiosurgery all play a role in the management of spinal metastases, and the indications and outcomes for each of these treatment options is discussed in the following chapter. With appropriate and timely intervention, the treatment of metastatic spine disease can be highly beneficial to the patient, with improvements seen in both quality of life and length of survival.


Vertebral Body Spinal Cord Compression Surgical Decompression Spinal Metastasis Spinal Instability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  1. 1.Vancouver General HospitalVancouverCanada

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