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Stem Cells and Cancer Stem Cells, Volume 4 pp 267–284Cite as

Proteomic Characterization of Mesenchymal Stem Cell-Like Populations Derived from Various Tissue Types

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Part of the book series: Stem Cells and Cancer Stem Cells ((STEM,volume 4))

Abstract

The evolution of proteomics has led to its application in identifying biomarkers of biological processes and pathways including signal transduction and cell development. Proteomic technologies are increasingly utilized to define the molecular mechanisms controlling mesenchymal stem/stromal cell (MSC) self-renewal, multipotency and fate. Bone marrow-derived MSCs are highly promising candidates in the field of regenerative medicine based on their high proliferative capacity, multi-lineage differentiation potential and immunomodulatory properties. Recently, equivalent MSC-like populations have also been isolated from adipose, dental and feto-maternal tissues. This chapter discusses the current technologies available for proteomic analysis and the studies performed on tissue-specific MSC-like populations to date.

K.M. Mrozik and J.Xiong are co-first authors

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Authors and Affiliations

  1. Colgate Australian Clinical Dental Research Centre, Dental School, The University of Adelaide, Adelaide, SA, 5005, Australia

    Krzysztof M. Mrozik, Jimin Xiong, Peter S. Zilm & P. Mark Bartold

  2. Division of Haematology/Hanson Institute and Center for Stem Cell Research, Robinson Institute, University of Medical and Veterinary science University of Adelaide, Adelaide, SA, Australia

    Stan Gronthos

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  1. Krzysztof M. Mrozik
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  2. Jimin Xiong
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Correspondence to Krzysztof M. Mrozik .

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    M.A. Hayat

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Mrozik, K.M., Xiong, J., Zilm, P.S., Gronthos, S., Bartold, P.M. (2012). Proteomic Characterization of Mesenchymal Stem Cell-Like Populations Derived from Various Tissue Types. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells, Volume 4. Stem Cells and Cancer Stem Cells, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2828-8_24

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