Skip to main content

Effect of Light Therapy of Blue LEDs Irradiation on Sprague Dawley Rat

  • Conference paper
  • First Online:
  • 1015 Accesses

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 107))

Abstract

In order to examine the healing effect of the blue light emitting diode (LED) irradiation on skin wounds, a round slice of wound 1 cm in diameter was cut on the back of the laboratory animal. Animals treated with blue light emitting diode (LED) irradiation (p < 0.05) healed at a faster rate than non-irradiated controls. The blue light emitting diode (LED) irradiated groups also had more collagen, according to Masson’s trichrome staining for collagen analysis. In conclusion, blue light emitting diode (LED) irradiation had a beneficial effect on wound healing and could probably replace low level laser therapy.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Mosman T (1983) Rapid colorimetric assay for cellular growth and survival : application to proliferation and cytotoxicity assay. J Immunol Method 65:55–63

    Article  Google Scholar 

  2. Polanyi TG, Bredemeier HC, Davis TW (1970) A CO2 laser for surgical research. Med Biol Eng 8:541–548

    Article  Google Scholar 

  3. Yahr WZ, Strully KT (1966) Blood vessel anastomosis by laser and other biomedical applications. J Assoc Adv Med Instrum 1:28–31

    Google Scholar 

  4. Beauvoit B, Kitai T, Chance B (1994) Correlation between the light scattering and the mitochondrial content of normal tissues and transplantable rodent tumors. Biophys 67:2501–2510

    Article  Google Scholar 

  5. Bisht D, Gupta SC, Misra V, Mital VP, Sharma P (1994) Effect of low intensity laser radiation on healing of open skin wounds in rats. Indian J Med Res 100:43–46

    Google Scholar 

  6. Sakurai Y, Yamaguchi M, Abiko Y (2000) Inhibitory effect of low-level laser irradiation on LPS-stimulated prostaglandin E2 production and cyclooxygenase-2 in human gingival fibroblasts. Eur J Oral Sci 108:29–34

    Article  Google Scholar 

  7. Whelan HT, Smits RLJ, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson BGL, Kane M, Chen G, Caviness J (2001) Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg 19:305–314

    Article  Google Scholar 

  8. Alena RAP, Medrado L, Pugliese S, Regina S, Andrade ZA (2003) Influence of low laser therapy on wound healing its biological action upon myofibroblasts. Laser Surg Med 32:239–244

    Article  Google Scholar 

  9. In de Braekt MMH, Van Alphen FAM, Kujipers-Jagtman AM, Maltha JC (1991) Effect of low level laser therapy on wound healing after palatal surgery in Beagle dogs. Lasers Surg Med 11:462–470

    Article  Google Scholar 

  10. Jiro I, Kenji K, Kuo I, Masakazu K, Chie S, Shigeru K (2000) Progress in retinal and eye research 19:113

    Google Scholar 

  11. Kana JS, Hutschenreiter G, Haina D, Waidelich W (1981) Effect of low-power density laser radiation on healing of open skin wounds in rats. Arch Surg 116:293–296

    Article  Google Scholar 

  12. Mester E, Spry T, Sender N, Tita J (1971) Effect of laser ray on wound healing. Amer J Surg 122:523–535

    Article  Google Scholar 

  13. Wong-Riley MT, Bai X, Buchamann E, Whelan HT (2001) Light-emitting diode treatment reverses the effect of TTX on cytochrome oxidase in neurons. Neuroreport 12:3033–3037

    Article  Google Scholar 

  14. Vinck EM, Cagnie BJ, Cornelissen MJ, Declercq HA, Cambier DC (2003) Increased fibroblast proliferation induced by light emitting diode and low power laser irradiation. Laser Med Sci 18:95–99

    Article  Google Scholar 

  15. Tada H, Shiho O, Kuroshima KI, Koyama M, Tsukamoto K (1986) An improved colorimetric assay for interleukin 2. J Immunol Methods 93:157–165

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Minwoo Cheon .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media B.V.

About this paper

Cite this paper

Kim, T., Park, Y., Lee, Y., Cheon, M. (2011). Effect of Light Therapy of Blue LEDs Irradiation on Sprague Dawley Rat. In: Park, J., Arabnia, H., Chang, HB., Shon, T. (eds) IT Convergence and Services. Lecture Notes in Electrical Engineering, vol 107. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2598-0_20

Download citation

  • DOI: https://doi.org/10.1007/978-94-007-2598-0_20

  • Published:

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-2597-3

  • Online ISBN: 978-94-007-2598-0

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics