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The Molecular Biology of Learning and Memory – Memory Phases and Signaling Cascades

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Book cover Honeybee Neurobiology and Behavior

Abstract

In species as diverse as mollusks, insects, birds, and mammals memories are highly dynamic and cover phases from seconds to a lifetime. In honey bees as in other species, the induction of distinct memory phases depends on parameters like the number and succession of the training trials. Employing techniques developed to monitor and manipulate the activity of signaling cascades in intact honey bees, training parameters could be linked to temporal modulations of signaling cascades that contribute to distinct memory phases. This analysis uncovered a dynamic network of signaling events in the antennal lobes (ALs) and the mushroom bodies (MBs) that are required for defined aspects of both, the induction and the maintenance of distinct memory phases.

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Abbreviations

eLTM:

Early phase LTM

lLTM:

Late phase LTM

LTM:

Long-term memory

MTM:

Mid-term memory

NO:

Nitric oxide

OA:

Octopamine

CS:

Conditioned stimulus

US:

Unconditioned stimulus

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Authors and Affiliations

  1. Natural Sciences and Technology III, Dept. 8.3 – Biosciences (Zoology and Physiology/Neurobiology), Saarland University, Saarbrücken, Germany

    Uli Müller

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  1. Uli Müller
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Correspondence to Uli Müller .

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Editors and Affiliations

  1. , Department of Neurobiology, Universität Konstanz, Universitätsstrasse 10, Konstanz, 78457, Germany

    C. Giovanni Galizia

  2. , Department of Neurobiology, Freie Universität Berlin, Königin-Luise-Str. 28-30, Berlin, 14195, Germany

    Dorothea Eisenhardt

  3. , Centre de Recherches sur la Cognition An, CNRS - Université Paul Sabatier, Route de Narbonne 118, Toulouse Cedex 9, 31062, France

    Martin Giurfa

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Müller, U. (2012). The Molecular Biology of Learning and Memory – Memory Phases and Signaling Cascades. In: Galizia, C., Eisenhardt, D., Giurfa, M. (eds) Honeybee Neurobiology and Behavior. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2099-2_31

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