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Pheromones and Adaptive Bystander-Mutagenesis in Mice

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Radiobiology and Environmental Security

Abstract

The genomic instability has been studied by cytogenetic analysis of chromosome aberrations in somatic and germ cells of CBA mouse strain. It was shown that volatile substances (VS) excreted by unisex groups of animals into the environment induce genomic instability in conspecifics of same sex depending on the state of VS-donors. Different pretreatments of donor animals modified the cytogenetic effect of their VS in recipients. The meaning of such pheromonal “bystander” effects for animal fitness is discussed.

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Acknowledgements

The research is supported by RFBR grant N 09-04-00693.

We are grateful to Prof. B. P. Surinov for his help in conducting our experiments with irradiation and to Dr. Alex Pryor from the Cambridge University (UK) for the manuscript correction.

Author information

Authors and Affiliations

  1. Department of Genetics & Breeding, Saint-Petersburg State University, Universitetskaya emb., 7/9, Saint-Petersburg, 199034, Russia

    Eugene V. Daev, Timofey S. Glinin & Anna V. Dukelskaya

Authors
  1. Eugene V. Daev
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  2. Timofey S. Glinin
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  3. Anna V. Dukelskaya
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Corresponding author

Correspondence to Eugene V. Daev .

Editor information

Editors and Affiliations

  1. , Medical Physics, McMaster University, Main Street West 1280, Hamilton, L8S 4 K1, Canada

    Carmel E. Mothersill

  2. Joint Institute for Nuclear Research, Dubna, Moscow Region, 141980, Russian Federation

    Victoria Korogodina

  3. , Department of Medical Physics, McMaster University, Main Street West 1280, Hamilton, L8S 4K1, Canada

    Colin B. Seymour

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© 2012 Springer Science+Business Media B.V.

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Daev, E.V., Glinin, T.S., Dukelskaya, A.V. (2012). Pheromones and Adaptive Bystander-Mutagenesis in Mice. In: Mothersill, C., Korogodina, V., Seymour, C. (eds) Radiobiology and Environmental Security. NATO Science for Peace and Security Series C: Environmental Security. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1939-2_14

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