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Stem Cells Like Astrocytes: Various Roles

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Book cover Stem Cells and Cancer Stem Cells, Volume 1

Part of the book series: Stem Cells and Cancer Stem Cells ((STEM,volume 1))

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Abstract

Adult stem cells have been identified in the brain, and continue to generate new neurons throughout life. These stem cells share a number of features with astrocytes, and recent evidence points to certain types of astrocytes capable of acquiring a stem-like phenotype. Stem cells have been implied as a potential origin for malignant glioma, especially glioblastoma multiforme (GBM), but are also known to react to a tumour by increased proliferation and migration towards the tumour mass. This apparent dichotomy between root and counteraction is discussed in this chapter, as well as the possibility of employing endogenous stem cells for brain cancer therapy.

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Authors and Affiliations

  1. Department of Neurosurgery, The Evelyn F. and William L. McKnight Brain Institute, University of Florida, PO Box 100265, Gainesville, FL, 32610-0015, USA

    Florian A. Siebzehnrubl

  2. Department of Neurosurgery, The Evelyn F. and William L. McKnight Brain Institute, University of Florida, Gainesville, FL, 32610-0015, USA

    Dennis A. Steindler

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  1. Florian A. Siebzehnrubl
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  2. Dennis A. Steindler
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Correspondence to Florian A. Siebzehnrubl .

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  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Siebzehnrubl, F.A., Steindler, D.A. (2012). Stem Cells Like Astrocytes: Various Roles. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells, Volume 1. Stem Cells and Cancer Stem Cells, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1709-1_3

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