Abstract
Among those who harbor no doubt that diabetes and malformations are associated some have held that the disease is associated with an increased frequency of all congenital malformations whereas others believe the increase is limited to some particular ones, especially or even the latter only. The former school was represented by Pedersen (1977, p. 196) although somewhat equivocally, when he said that “no specific defect is peculiar to diabetes, but severe congenital heart disease and skeletal deformity are characteristic.” The latter school, less hesitantly, favored a number of abnormalities, among them of course caudal dysplasia, but also holoprosencephaly, neural tube defects, and cardiovascular malformations. This chapter will look into these assertions.
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© 2012 Springer Science+Business Media B.V.
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Kalter, H. (2012). Specific Congenital Malformations. In: A History of Diabetes in Pregnancy. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1557-8_16
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DOI: https://doi.org/10.1007/978-94-007-1557-8_16
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Publisher Name: Springer, Dordrecht
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Online ISBN: 978-94-007-1557-8
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