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Triazoles

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Microwave-Induced Synthesis of Aromatic Heterocycles

Part of the book series: SpringerBriefs in Molecular Science ((GREENCHEMIST,volume 3))

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Abstract

Triazole and its derivatives belong to a class of exceptionally active compounds possessing a wide spectrum of chemotherapeutic activities, including anticonvulsant, antimicrobial, antihypertensive, analgesic, antiviral, antioxidant, anti-inflammatory, antitumor and anti-HIV activity. In addition, it was reported that compounds having triazole moieties, such as vorozole, letrozole and anastrazole appeared to be very effective aromatase inhibitors, which in turn prevented breast cancer. Apart from their pharmacological significance triazole derivatives exhibit interesting chemical properties. The ability of triazoles to form a bridge between metal ions makes such ligands very important for magnetochemical applications. Some complexes containing substituted triazole ligands have potential uses as optical sensors or molecular-based memory devices. The synthesis of this heterocyclic moiety under microwave conditions is described in this chapter.

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Authors and Affiliations

  1. Department of Chemistry, Aligarh Muslim University, Aligarh, India

    Abdul Rauf

  2. B-1, Liberty Homes, Opposite Abdullah College, Marris Road, Aligarh, 202 002, India

    Nida Nayyar Farshori

Authors
  1. Abdul Rauf
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  2. Nida Nayyar Farshori
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Correspondence to Abdul Rauf .

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Rauf, A., Farshori, N.N. (2012). Triazoles. In: Microwave-Induced Synthesis of Aromatic Heterocycles. SpringerBriefs in Molecular Science(), vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1485-4_8

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