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Brain Tumors: Quality of Life

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Tumors of the Central Nervous system, Volume 3

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 3))

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Abstract

Brain tumors and their treatment may have significant physical, cognitive, emotional and social effects on patients. Patients affected by brain tumors frequently exhibit poor quality of life (QoL) because of tumor symptoms, diagnostic examinations, way of communication of the diagnosis and treatments. In brain tumor patients, palliating symptoms and maintaining or improving Health-Related quality of life is particularly relevant. This chapter will analyze several aspects related to QoL in patients affected by brain tumors.

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References

  • Anderson SI, Taylor R, Whittle IR (1999) Mood disorders in patients after treatment for primary intracranial tumours. Br J Neurosurg 13:480–485

    PubMed  CAS  Google Scholar 

  • Arnold SD, Forman LM, Brigidi BD, Carter KE, Schweitzer HA, Quinn HE, Guill AB, Herndon JE 2nd, Raynor RH (2008) Evaluation and characterization of generalized anxiety and depression in patients with primary brain tumors. Neuro-oncology 10:171–181

    Article  PubMed  Google Scholar 

  • Bampoe J, Laperriere N, Pintilie M, Glen J, Micallef J, Bernstein M (2000) Quality of life in patients with glioblastoma multiforme participating in a randomised study of brachytherapy as a boost treatment. J Neurosurg 93:917–926

    Article  PubMed  CAS  Google Scholar 

  • Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J (1993) The functional assessment of cancer therapy (FACT) scale: development and validation of the general measure. J Clin Oncol 11:570–579

    PubMed  CAS  Google Scholar 

  • D’Angelo C, Mirijello A, Leggio L, Ferrulli A, Carotenuto V, Scolaro N, Miceli A, D’Angelo V, Gasbarrini G, Addolorato G (2008) State and trait anxiety and depression in patients with primary brain tumors before and after surgery: 1-year longitudinal study. J Neurosurg 108:281–286

    Article  PubMed  Google Scholar 

  • de Haes J, Curran D, Young T, Bottomley A, Flechtner H, Aaronson N, Blazeby J, Bjordal K, Brandberg Y, Greimel E, Maher J, Sprangers M, Cull A (2000) Quality of life evaluation in oncological clinical trials-the EORTC model. The EORTC Quality of Life Study Group. Eur J Cancer 36:821–825

    Google Scholar 

  • Giesinger JM, Golser M, Erharter A, Kemmler G, Schauer-Maurer G, Stockhammer G, Muigg A, Hutterer M, Rumpold G, Holzner B (2009) Do neurooncological patients and their significant others agree on quality of life ratings?. Health Qual Life Outcomes 7:87

    Article  PubMed  Google Scholar 

  • Giovagnoli AR (1999) Quality of life in patients with stable disease after surgery, radiotherapy, and chemotherapy for malignant brain tumour. J Neurol Neurosurg Psychiatry 67:358–363

    Article  PubMed  CAS  Google Scholar 

  • Giovagnoli AR, Silvani A, Colombo E, Boiardi A (2005) Facets and determinants of quality of life in patients with recurrent high grade glioma. J Neurol Neurosurg Psychiatry 76:562–568

    Article  PubMed  CAS  Google Scholar 

  • Heimans JJ, Taphoorn MJB (2002) Impact of brain tumour treatment on quality of life. J Neurol 249:955–960

    Article  PubMed  Google Scholar 

  • Kaplan CP, Miner ME (2000) Relationships: importance for patients with cerebral tumours. Brain Inj 14:251–259

    Article  PubMed  CAS  Google Scholar 

  • Klein M, Taphoorn MJB, Heimans JJ, Van der Ploeg HM, Vandertop WP, Smit EF, Leenstra S, Tulleken CAF, Boogerd W, Belderbos JSA, Cleijne W, Aaronson NK (2001) Neurobehavioral status and health-related quality of life in newly diagnosed high-grade glioma patients. J Clin Oncol 19:4037–4047

    PubMed  CAS  Google Scholar 

  • Locke DE, Decker PA, Sloan JA, Brown PD, Malec JF, Clark MM, Rummans TA, Ballman KV, Schaefer PL, Buckner JC (2007) Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients. J Pain Symptom Manage 34:628–638

    Article  PubMed  Google Scholar 

  • Mackworth N, Fobair P, Prados MD (1992) Quality of life self-reports from 200 brain tumor patients: comparisons with Karnofsky performance scores. J Neurooncol 14:243–253

    Article  PubMed  CAS  Google Scholar 

  • Moots PL (1998) Pitfalls in the management of patients with malignant gliomas. Semin Neurol 18:257–265

    Article  PubMed  CAS  Google Scholar 

  • Muldoon MF, Barger SD, Flory JD, Manuck SB (1998) What are quality of life measurements measuring? Br Med J 316:542–545

    CAS  Google Scholar 

  • Osoba D, Aaronson NK, Muller M, Sneeuw K, Hsu MA, Yung WKA, Brada M, Newlands E (1996) The development and psychometric validation of a brain cancer quality-of-life questionnaire for use in combination with general cancer-specific questionnaires. Qual Life Res 5:139–150

    Article  PubMed  CAS  Google Scholar 

  • Osoba D, Aaronson NK, Muller M, Sneeuw K, Hsu MA, Yung WKA, Brada M, Newlands E (1997) Effect of neurological dysfunction on health-related quality of life in patients with highgrade malignant glioma. J Neurooncol 34:263–278

    Article  PubMed  CAS  Google Scholar 

  • Osoba D, Brada M, Yung WKA, Prados M (2000a) Health-related quality of life in patients treated with temozolamide versus procarbazine for recurrent glioblastoma multiforme. J Clin Oncol 18:1481–1491

    PubMed  CAS  Google Scholar 

  • Osoba D, Brada M, Yung WKA, Prados MD (2000b) Health-related quality of life in patients with anaplastic astrocytomas during treatment with temozolomide. Eur J Cancer 36:1788–1795

    Article  PubMed  CAS  Google Scholar 

  • Ottawa Charter for Health Promotion (1986) WHO/HPR/HEP/95.1. WHO, Geneva

    Google Scholar 

  • Pelletier G, Verhoef MJ, Khatri N, Hagen N (2002) Quality of life in brain tumor patients: the relative contributions of depression, fatigue, emotional distress, and existential issues. J Neurooncol 57:41–49

    Article  PubMed  Google Scholar 

  • Orley J, Kuyken W (eds) (1994) Quality of life assessment: international perspectives. Proceedings of the joint meeting organized by the world health organization and the foundation IPSEN in Paris, 2–3 July 1993. Springer, Berlin

    Google Scholar 

  • Recht L, Glantz M, Chamberlain M, Hsieh CC (2003) Quantitative measurement of quality outcome in malignant glioma patients using an independent living score (ILS). Assessment of a retrospective cohort. J Neurooncol 61:127–136

    Article  PubMed  CAS  Google Scholar 

  • Reijneveld JC, Sitskoorn MM, Klein M, Nuyen J, Taphoorn MJB (2001) Cognitive status and quality of life in patients with suspected versus proven low-grade gliomas. Neurology 56:618–623

    PubMed  CAS  Google Scholar 

  • Taphoorn MJB, Schiphorst AK, Snoek FJ, Lindeboom J, Wolbers JG, Karim ABMF, Huijgens PC, Heimans JJ (1994) Cognitive functions and quality of life in patients with low-grade gliomas: the impact of radiotherapy. Ann Neurol 36:48–54

    Article  PubMed  CAS  Google Scholar 

  • Ware JE, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36): I conceptual framework and item selection. Med Care 30:473–483

    Article  PubMed  Google Scholar 

  • Weitzner MA, Meyers CA, Byrne K (1996) Psychosocial functioning and quality of life in patients with primary brain tumors. J Neurosurg 84:29–34

    Article  PubMed  CAS  Google Scholar 

  • Weitzner MA, Meyers CA, Gelke CK, Byrne KS, Cella DF, Levin VA (1995) The functional assessment of cancer therapy (FACT) scale. development of a brain subscale and revalidation of the general version (FACT-G) in patients with primary brain tumors. Cancer 75:1151–1161

    CAS  Google Scholar 

  • WHO (1996) What quality of life? The WHOQOL Group. World health organization quality of life assessment. World Health Forum 17:354–356 (Geneva, World Health Organization)

    Google Scholar 

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Correspondence to Cristina D’Angelo .

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D’Angelo, C., Mirijello, A., Addolorato, G., D’Angelo, V.A. (2011). Brain Tumors: Quality of Life. In: Hayat, M. (eds) Tumors of the Central Nervous system, Volume 3. Tumors of the Central Nervous System, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1399-4_31

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  • DOI: https://doi.org/10.1007/978-94-007-1399-4_31

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  • Publisher Name: Springer, Dordrecht

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