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Tumors of the Central Nervous system, Volume 3 pp 279–285Cite as

Stereotactic Radiosurgery for Cerebral Metastases of Digestive Tract Tumors

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Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 3))

Abstract

Cerebral metastases account for the majority of intracranial tumors. Digestive system malignancies contribute 3–8% of cerebral metastases and represent a late complication of systemic disease. Stereotactic radiosurgery employs linear accelerator technology (Linac) or multi-cobalt sources (Gamma Knife) to deliver a high dose of focal radiation to a precise target. The efficacy of stereotactic radiosurgery in treating brain metastases has been established in numerous clinical trials with reports of durable local control and median survival times of 7–12 months. To date, 3 significant retrospective studies have described the clinical outcomes, prognostic factors, tumor control rates and complications associated with stereotactic radiosurgical treatment of brain metastases from gastrointestinal cancer. Herein the authors explicate the natural history of digestive system cerebral metastases and describe the retrospective analyses that demonstrate utility of stereotactic radiosurgery in tumor control.

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Authors and Affiliations

  1. Department of Neurological Surgery, Health Sciences Center, Charlottesville, VA, 22908, USA

    Jesse J. Savage & Jason P. Sheehan

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  1. Jesse J. Savage
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  2. Jason P. Sheehan
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Correspondence to Jason P. Sheehan .

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Editors and Affiliations

  1. , Kean University, Department of Biological Sciences, Morris Avenue 1000, UNION, 07083, New Jersey, USA

    M.A. Hayat

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Savage, J.J., Sheehan, J.P. (2011). Stereotactic Radiosurgery for Cerebral Metastases of Digestive Tract Tumors. In: Hayat, M. (eds) Tumors of the Central Nervous system, Volume 3. Tumors of the Central Nervous System, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1399-4_29

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  • DOI: https://doi.org/10.1007/978-94-007-1399-4_29

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-1398-7

  • Online ISBN: 978-94-007-1399-4

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