Abstract
This review provides an overview of the biology of hemangiopericytomas as well as an overview of currently available treatment regimens for this highly vascular lesion. While extirpation is the gold standard for diagnosis, tumor control, and relief of mass effect, the high recurrence rate of this tumor type in addition to its proximity to venous channels or skull base locations, can makes resection much less re-resection less attractive. Therefore, stereotactic radiosurgery principally with the Gamma Knife has been used to deliver a steep dose gradient and minimizes the radiation delivered to the surrounding areas. Hence, it becomes possible to deliver a significantly larger and presumably more biologically effective dose to the tumor while limiting the side effects of radiation to normal brain tissue. These characteristics make Gamma Knife radiosurgery (GKS) a very useful tool in treating patients with recurrent hemangiopericytoma or tumors in surgically inaccessible locations.
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Sheehan, J.P., Marchan, E.M. (2011). Intracranial Hemangiopericytoma: Gamma Knife Surgery. In: Hayat, M. (eds) Tumors of the Central Nervous system, Volume 3. Tumors of the Central Nervous System, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1399-4_28
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DOI: https://doi.org/10.1007/978-94-007-1399-4_28
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