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Computational techniques for selection of biomaterial scaffolds for tissue engineering

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Book cover Advances on Modeling in Tissue Engineering

Part of the book series: Computational Methods in Applied Sciences ((COMPUTMETHODS,volume 20))

Abstract

Computational tools are nowadays an indispensable tool for engineering design. Tissue engineering is an interdisciplinary field which so far has been mainly limited to experimental investigations. Here we present several examples of how computer models can be used in the design of tissue engineering scaffolds. Investigations of the effect of scaffold porosity, dissolution rate and/or scaffold material properties on processes such as cell differentiation, migration and angio genesis are presented. Current limitations and future perspectives in the develop ment and potential application of these models are described.

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Author information

Authors and Affiliations

  1. Trinity Centre for Bioengineering, School of Engineering, Trinity College, Dublin, Ireland

    S. Checa, D. P. Byrne, D. J. Kelly & P. J. Prendergast

  2. Institute for Bioengineering of Catalonia, Barcelona, Spain

    C. Sandino & D. Lacroix

Authors
  1. S. Checa
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  2. C. Sandino
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  3. D. P. Byrne
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  4. D. J. Kelly
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  5. D. Lacroix
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  6. P. J. Prendergast
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Corresponding author

Correspondence to S. Checa .

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Editors and Affiliations

  1. IDMEC – Instituto de Engenharia Mecânica, Instituto Superior Técnico, Av. Rovisco Pais 1, Lisboa, 1049-001, Portugal

    Paulo R. Fernandes

  2. Polytechnic Institute of Leiria, Centre for Rapid and Sustainable Product, Leiria, Portugal

    Paulo Jorge Bártolo

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Checa, S., Sandino, C., Byrne, D.P., Kelly, D.J., Lacroix, D., Prendergast, P.J. (2011). Computational techniques for selection of biomaterial scaffolds for tissue engineering. In: Fernandes, P., Bártolo, P. (eds) Advances on Modeling in Tissue Engineering. Computational Methods in Applied Sciences, vol 20. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1254-6_4

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  • DOI: https://doi.org/10.1007/978-94-007-1254-6_4

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-1253-9

  • Online ISBN: 978-94-007-1254-6

  • eBook Packages: EngineeringEngineering (R0)

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