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Environmental Security and Ecoterrorism pp 117–127Cite as

Environmental and Human Health Issues of Silver Nanoparticles Applications

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Abstract

The significant growth in applications of silver nanoparticles across ­various branches of industry as well as in consumer products has caused concerns that nanosilver may have a toxic effect on the environment and human health and may have implications for eco-terorism. This paper presents research on antimicrobial effects of silver nanoparticles. We studied the cytotoxicity of silver nanoparticles via an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromid) assay that measures cell activity through the mitochondrial cleavage of a molecule that exhibits a change of colour that can be measured spectrophotometrically. NIH-3T3 (Swiss mouse embryo), HEP-G2 (human hepatocellular carcinoma), A-549 (human lung carcinoma), PC-12 (rat adrenal pheochromocytoma), and Colo-320 (human colon adenocarcinoma) cells were chosen in order to study different possible absorption paths of nanoparticles into the organism and various areas of particle accumulation in the body. The obtained MTT test results have shown that silver nanoparticles with concentrations of ∼1–10 ppm entering the body from air or liquid suspensions can present a potential risk to human health.

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Author information

Authors and Affiliations

  1. Institute of Nuclear Physics, Tashkent, Uzbekistan

    Renat R. Khaydarov & Rashid A. Khaydarov

  2. V.N. Sukachev Institute of Forest SB RAS, Krasnoyarsk, Russia

    Svetlana Evgrafova

  3. Institute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University, Hannover, Germany

    Stefanie Wagner

  4. Department of Environmental Engineering, Yonsei University, Wonju, South Korea

    Seung Y. Cho

Authors
  1. Renat R. Khaydarov
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  2. Rashid A. Khaydarov
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  3. Svetlana Evgrafova
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  4. Stefanie Wagner
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  5. Seung Y. Cho
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Corresponding author

Correspondence to Renat R. Khaydarov .

Editor information

Editors and Affiliations

  1. Food Engineering Dept., Middle East Technical University, Ankara, 06531, Turkey

    Hami Alpas

  2. , Institute of Earth Sciences, Hebrew University of Jerusalem, Safra Givat Ram Campus, Jerusalem, Israel

    Simon M. Berkowicz

  3. , Inst. of Higher Nervous Activity of RAS, Inst. of Russian Academy of Sciences, Moscow, Russian Federation

    Irina Ermakova

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© 2011 Springer Science+Business Media B.V.

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Khaydarov, R.R., Khaydarov, R.A., Evgrafova, S., Wagner, S., Cho, S.Y. (2011). Environmental and Human Health Issues of Silver Nanoparticles Applications. In: Alpas, H., Berkowicz, S., Ermakova, I. (eds) Environmental Security and Ecoterrorism. NATO Science for Peace and Security Series C: Environmental Security. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1235-5_9

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