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Advanced Imaging In Coronary Artery Disease pp 273–287Cite as

Study of Cardiac Function with PET or SPECT

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 202))

Abstract

The measurement and knowledge of myocardial function is extremely important for the diagnostic and prognostic assessment of the cardiac patient. It is well known, for example, that the likelihood of 1-year survival after myocardial infarction is directly and exponentially proportional to the value of the resting left ventricular ejection fraction (LVEF)1. Measurement of myocardial function has traditionally been implemented with planar nuclear (first pass, gated blood pool) and planar non-nuclear techniques (echocardiography, contrast ventriculography), as well as, more recently, with tomographic nuclear (gated perfusion SPECT, gated blood pool SPECT, gated PET) and tomographic non-nuclear techniques (cine MRI, cine CT). Of all these techniques, only gated perfusion SPECT and PET offer the opportunity to simultaneously acquire information on both the perfusion and the function of the left ventricle, and to do it in threedimensional and quantitative fashion. Since it is increasingly being reported that the knowledge of global LVEF provides incremental prognostic value over that of myocardial perfusion alone2, gated perfusion SPECT and PET are likely to be increasingly utilized in this era of health care cost containment and emphasis on outcomes, and will represent the main focus of this chapter. The myocardial function parameters obtainable from gated perfusion SPECT and gated PET are LVEF, regional (segmental) myocardial wall motion and wall thickening. Before addressing each of them in detail, it is appropriate to briefly describe the acquisition of a gated SPECT or PET study.

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Authors
  1. Guido Germano
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Editor information

Editors and Affiliations

  1. Department of Cardiology, Leiden University Medical Center Leiden, Leiden, The Netherlands

    Ernst E. Van Der Wall

  2. Department of Cardiology, University Hospital Groningen, Groningen, The Netherlands

    Paul K. Blanksma  & Harry J. G. M. Crijns  & 

  3. Department of Cardiology, Martini Hospital, Groningen, The Netherlands

    Menco G. Niemeyer

  4. PET-center, University Hospital Groningen, Groningen, The Netherlands

    Willem Vaalburg

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© 1998 Springer Science+Business Media New York

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Germano, G. (1998). Study of Cardiac Function with PET or SPECT. In: Van Der Wall, E.E., Blanksma, P.K., Niemeyer, M.G., Vaalburg, W., Crijns, H.J.G.M. (eds) Advanced Imaging In Coronary Artery Disease. Developments in Cardiovascular Medicine, vol 202. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0866-2_17

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  • DOI: https://doi.org/10.1007/978-94-007-0866-2_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3746-4

  • Online ISBN: 978-94-007-0866-2

  • eBook Packages: Springer Book Archive

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