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Chiral aminals in asymmetric synthesis

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Advanced Asymmetric Synthesis

Abstract

Aminals are the nitrogen equivalents of acetals.1 Acyclic aminals are not usually very stable. In contrast, the cyclic ones are stable compounds in neutral and basic media. Particularly attractive as reagents are the 5-membered ring systems (imidazolidine ring), because of the availability of chiral 1, 2-diamines and the ease of hydrolysis back to the aldehyde, which can be done under very mild acidic conditions.

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Authors
  1. A. Alexakis
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  2. P. Mangeney
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Editor information

Editors and Affiliations

  1. School of Chemical Sciences, University of East Anglia, Norwich, UK

    G. R. Stephenson

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© 1996 Springer Science+Business Media Dordrecht

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Alexakis, A., Mangeney, P. (1996). Chiral aminals in asymmetric synthesis. In: Stephenson, G.R. (eds) Advanced Asymmetric Synthesis. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0797-9_5

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  • DOI: https://doi.org/10.1007/978-94-007-0797-9_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3731-0

  • Online ISBN: 978-94-007-0797-9

  • eBook Packages: Springer Book Archive

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