Abstract
The field of conjugate addition reactions is a vast one. A book1 and several excellent reviews2 have appeared over the last few years, which cover most aspects of conjugate addition reactions. The focus in this chapter will be mainly on the use of non-racemic3 additives, e.g. ligands and/or catalysts, in asymmetric conjugate additions. The chapter begins with a brief introduction to the chemistry of conjugate additions. After this it is organized according to the class of nucleophile or incipient nucleophile.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Perlmutter, P., Conjugate Addition Reactions in Organic Synthesis,Pergamon Press, Oxford, 1992.
Rossiter, B.E. and Swingle, N.M., Chem. Rev., 1992, 92, 771; (b) Lee, V.J., in Comprehensive Organic Synthesis,Trost, B.M. and Fleming, I. (eds), Pergamon Press, Oxford, 1991.
Heathcock, C.H., Finkelstein, B.L., Jarvi, E.T, Radel, P.A. and Hadley, C.R, J. Org. Chem., 1988, 53, 1922.
Chapdelaine, M. J. and Hulee, M, Org. React., 1990, 38, 225.
Rossiter, B.E. and Eguchi, M., Tetrahedron Lett, 1990, 31, 965.
Swingle, N.M., Reddy, K.V. and Rossiter, B.E., Tetrahedron, 1994, 50, 4455.
Tanaka, K. and Suzuki, H., J. Chem. Soc, Chem. Commun., 1991, 101; (b) Tanaka, K., Ushio, H. and Suzuki, H., J. Chem. Soc, Chem. Commun.,1990, 795.
Leyendecker, F. and Laucher, D., Nouv. J. Chim., 1985, 9, 13; (b) Leyendecker, F. and Laucher, D., Tetrahedron Lett.,1983, 24, 3517.
Alexakis, A., Frutos, J. and Mangeney, P., Tetrahedron: Asymmetry, 1993, 4, 2427; (b) Alexakis, A., Mutti, S. and Normant, J.F., J. Am. Chem. Soc,1991, 113,6332.
Ashby, E.C., Lin, J. J. and Watkins, J.J., J. Org. Chem., 1977, 42, 1099.
Ahn, K.-H., Klassen, R.B. and Lippard, S.J., Organometallics, 1990, 9, 3178; (b) Villacorta, G.M., Pulla Rao, Ch. and Lippard, S.J., J. Am. Chem. Soc,1988, 110,3175.
Zhou, Q.-L. and Pfaltz, A., Tetrahedron, 1994, 50, 4467.
van Koten, G., Pure Appl. Chem., 1994, 66, 1455.
Gilman, H. and Kirby, R.H., J. Am. Chem. Soc., 1941, 63, 2046.
Petrier, C, Barbosa, J.C. de S., Dupuy, C. and Luche, J.-L., J. Org. Chem., 1985, 50, 5761.
de Vries, A.H.M., Jansen, J.F.G.A. and Feringa, B.L., Tetrahedron, 1994, 50, 4479.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Perlmutter, P. (1996). Asymmetric conjugate addition reactions. In: Stephenson, G.R. (eds) Advanced Asymmetric Synthesis. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0797-9_11
Download citation
DOI: https://doi.org/10.1007/978-94-007-0797-9_11
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3731-0
Online ISBN: 978-94-007-0797-9
eBook Packages: Springer Book Archive