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Glioma Grading Using Cerebral Blood Volume Heterogeneity

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Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 1))

Abstract

Treatment of tumors of the central nervous system (CNS) constitutes a considerable challenge in spite of important advances in surgery, radiotherapy and chemotherapy. The majority of malignant brain tumors make up a heterogeneous group of vascular neoplasms known as gliomas. According to the 2008 Central Brain Tumor Registry of the United States, gliomas account for 36% of all brain tumors and 81% of all malignant brain tumors. Using the World Health Organization (WHO) criteria, the conventional method for diagnosing glioma patients is based on histopathological evaluation of tissue samples from surgery. Here, gliomas are graded according to the degree of malignancy (I-IV) of which grades I-II represent low-grade gliomas, whereas grades III-IV represent high-grade gliomas.

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Acknowledgments

The authors thank John K Hald, Division for Diagnostics and Intervention, Rikshospitalet, Oslo University Hospital, N-0027 Oslo, Norway

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Correspondence to Kyrre E. Emblem .

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Emblem, K.E., Bjornerud, A. (2011). Glioma Grading Using Cerebral Blood Volume Heterogeneity. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 1. Tumors of the Central Nervous System, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0344-5_4

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  • DOI: https://doi.org/10.1007/978-94-007-0344-5_4

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