Flow of a Blood Analogue Solution Through Microfabricated Hyperbolic Contractions

  • P. C. Sousa
  • I. S. Pinho
  • F. T. Pinho
  • M. S. N. OliveiraEmail author
  • M. A. Alves
Part of the Computational Methods in Applied Sciences book series (COMPUTMETHODS, volume 19)


The flow of a blood analogue solution past a microfabricated hyperbolic contraction followed by an abrupt expansion was investigated experimentally. The shape of the contraction was designed in order to impose a nearly constant strain rate to the fluid along the centerline of the microgeometry. The flow patterns of the blood analogue solution and of a Newtonian reference fluid (deionized water), captured using streak line imaging, are quite distinct and illustrate the complex behavior of the blood analogue solution flowing through the microgeometry. The flow of the blood analogue solution shows elastic-driven effects with vortical structures emerging upstream of the contraction, which are absent in Newtonian fluid flow. In both cases the flow also develops instabilities downstream of the expansion but these are inertia driven. Therefore, for the blood analogue solution at high flow rates the competing effects of inertia and elasticity lead to complex flow patterns and unstable flow develops.


Blood analogue fluid Extensional flow Microfluidics Viscoelasticity Flow visualization Hyperbolic contraction 



The authors gratefully acknowledge funding by FCT via projects PTDC/EQU-FTT/71800/2006, REEQ/262/EME/2005, REEQ/928/EME/2005, PTDC/EME-MFE/099109/2008 and PTDC/EQU-FTT/70727/2006. In addition, PCS and ISP acknowledge the financial support of scholarships SFRH/BD/28846/2006 and CEFT/BII/2008/01.


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • P. C. Sousa
    • 1
  • I. S. Pinho
    • 1
  • F. T. Pinho
    • 2
  • M. S. N. Oliveira
    • 1
    Email author
  • M. A. Alves
    • 1
  1. 1.Departamento de Engenharia Química, Centro de Estudos de Fenómenos de TransporteFaculdade de Engenharia da Universidade do PortoPortoPortugal
  2. 2.Centro de Estudos de Fenómenos de Transporte, Departamento de Engenharia MecânicaFaculdade de Engenharia da Universidade do PortoPortoPortugal

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