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International Handbook of Adult Mortality pp 381–398Cite as

Links Between Biomarkers and Mortality

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Part of the book series: International Handbooks of Population ((IHOP,volume 2))

Abstract

A biomarker is an objectively measured indicator of a physiological state. Biomarkers include indicators of genotype, normal biological processes, pathogenic processes, and pharmacologic responses to a therapeutic intervention (Biomarkers Definitions Working Group 2001; National Heart Lung and Blood Institute 2007). Biomarkers can serve as objective indicators of health status within a sample, indicators of health change over time, and, with comparable measurement, indicators of differences across populations. They signal disease status, early physiological dysregulation preceding disease, or change in organ reserve or functioning. And they can clarify how the social, psychological, and behavioral factors traditionally examined in social science research get under the skin to influence biology and subsequent health outcomes (Crimmins and Seeman 2001, 2004; Crimmins et al. 2008a; Seeman and Crimmins 2001).

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Acknowledgments

Support for this research was provided by NIH Grants P30 AG017265, T32 AG0037, and the USC Oakley Fellowship Fund.

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  1. Department of Gerontology, Davis School of Gerontology, Andrus Gerontology Center, University of Southern California, Los Angeles, CA, 90089, USA

    Eileen M. Crimmins

  2. Office of Population Research, Princeton University, 263 Wallace Hall, Princeton, NJ, 08544, USA

    Sarinnapha Vasunilashorn (Postdoctoral Fellow)

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Correspondence to Eileen M. Crimmins .

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  1. Dept. Sociology, University of Colorado, Boulder, Boulder, 80309-0327, Colorado, USA

    Richard G. Rogers

  2. Davis School of Gerontology, Andrus Gerontology Center, University of Southern California, McClintock Ave. 3715, Los Angeles, 90089-0191, California, USA

    Eileen M. Crimmins

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Crimmins, E.M., Vasunilashorn, S. (2011). Links Between Biomarkers and Mortality. In: Rogers, R., Crimmins, E. (eds) International Handbook of Adult Mortality. International Handbooks of Population, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9996-9_18

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