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Broadband Analysis of Bioagents by Mass Spectrometry

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Detection of Biological Agents for the Prevention of Bioterrorism

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Abstract

Mass spectrometry was first reported to provide analysis of intact metabolite biomarkers from whole cells in 1975.1 Since then advances in ionization techniques have extended our capabilities to polar lipids and, eventually, to proteins.2, 3 Mass spectrometry provides a broadband detection system, which, however, has great specificity. Bioinformatics plays an important role in providing flexible and rapid characterization of species, based on protein and peptide mass spectra collected in the field.

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Authors and Affiliations

  1. Departments of Chemistry and Biochemistry, College of Chemical and Life Sciences, University of Maryland, College Park, MD, 20742, USA

    Catherine Fenselau, Colin Wynne & Nathan Edwards

Authors
  1. Catherine Fenselau
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  2. Colin Wynne
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  3. Nathan Edwards
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Corresponding author

Correspondence to Catherine Fenselau .

Editor information

Editors and Affiliations

  1. , Science Branch, Fisheries and Oceans Canada, St. John's, A1C 5X1, Newfoundland and Labrador, Canada

    Joseph Banoub

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Fenselau, C., Wynne, C., Edwards, N. (2011). Broadband Analysis of Bioagents by Mass Spectrometry. In: Banoub, J. (eds) Detection of Biological Agents for the Prevention of Bioterrorism. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9815-3_1

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