Abstract
Cells have two main means at their disposal for regulating their metabolic reaction rates: 1. They can use small molecules for certain target enzymes, which as a rule belong to a certain class of proteins, the allosteric enzymes. These ligands bring about conformational changes which result sometimes in a lower enzyme activity (allosteric inhibition) and sometimes in a higher (allosteric activation). 2. The presence of essential metabolites in the cytoplasm at a certain concentration causes the repression, at the level of transcription, of the biosynthesis of enzymes leading to the biosynthesis of such metabolite.
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Cohen, G.N. (2010). Regulation of the Biosynthesis of the Amino Acids of the Aspartic Acid Family in Enterobacteriaceae . In: Microbial Biochemistry. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9437-7_26
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DOI: https://doi.org/10.1007/978-90-481-9437-7_26
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