Abstract
We launched the genometastases hypothesis in 1999 with the following words: “Metastasis might occur via transfection of susceptible cells, located in distant target organs, with dominant oncogenes that are derived from the primary tumor and are circulating in the plasma”. The different experiments performed thereafter, gave more plausibility to the idea. In this article we summarized the history of the hypothesis and the future as a consistent theory.
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García-Olmo, D.C., Guadalajara, H., Dominguez-Berzosa, C., Picazo, M.G., García-Arranz, M., García-Olmo, D. (2010). Functionality of CNAPS in Cancer: The Theory of Genometastasis. In: Gahan, P. (eds) Circulating Nucleic Acids in Plasma and Serum. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9382-0_15
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DOI: https://doi.org/10.1007/978-90-481-9382-0_15
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