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Actin-based Chromosome Movements in Cell Division

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Actin-based Motility

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Abstract

Although microtubules are well-studied players moving chromosomes during mitosis and meiosis, recent work in mammalian oocytes has revealed intricate interactions between actin and chromosomes that directly control the positioning and extrusion of chromosomes during asymmetric meiotic cell divisions. New evidence also suggests that actin and actin-based motor proteins play interesting roles in the assembly and orientation of both meiotic and mitotic spindles. In this chapter we review what is known to date in this emerging area of actin-based motility and discuss outstanding questions and key mechanistic issues for future study.

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Acknowledgement

The author would like to thank Marie-Helene Verlhac for her corrections and suggestions on the manuscript.

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  1. Stowers Institute for Medical Research, 1000 East 50th street, Kansas City, MO, 64110, USA

    Rong Li

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  1. Rong Li
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Correspondence to Rong Li .

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  1. , Laboratory of Structural Enzymology and, CNRS, Gif-sur-Yvette Cedex, 91198, France

    Marie-France Carlier

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Li, R. (2010). Actin-based Chromosome Movements in Cell Division. In: Carlier, MF. (eds) Actin-based Motility. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9301-1_7

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