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Flavivirus

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PCR for Clinical Microbiology

Abstract

The Flaviviruses responsible for most cases of encephalitis in Australia and South East Asia include Murray Valley Encephalitis virus, Kunjin virus, Japanese B Encephalitis virus and West Nile virus. Flavivirus infection is usually diagnosed by the detection of virus-specific IgM antibody or by measuring a rising titre of IgG antibodies in the acute phase of illness. Local IgM antibody can also be detected in the CSF of patients with CNS disease. Because many infections with flaviviruses are inapparent, caution should be exercised in the interpretation of serological results. Patients may also have viral RNA in the blood or CSF and its presence constitutes a definite indicator of current infection.

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Acknowledgments

We would like to thank Eileen J. Pratt for valuable technical assistance provided.

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Correspondence to Gerald B. Harnett .

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© 2010 Springer Science+Business Media B.V.

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Harnett, G.B., Cattell, J.A. (2010). Flavivirus. In: Schuller, M., Sloots, T., James, G., Halliday, C., Carter, I. (eds) PCR for Clinical Microbiology. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9039-3_34

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