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Linoleic Acid is Protective

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Abstract

Linoleic acid (18:2 ω-6, LA) has been known since 1956 to be one dietary component that lowers serum total and LDL-cholesterol, hence risk of CHD. It has taken time before becoming clear that LA itself, in diet or in plasma lipids is inversely related to CHD incidence. Evidence has accumulated gradually (Table 25.1), culminating in results from the large US Nurses Cohort (1997). LA also appears to reduce the tendency to thrombosis and risk of dangerous cardiac arrhythmias.

LA is not a precursor of arachidonic acid (potentially thrombogenic) at ordinary intake levels and fears that it interferes with conversion of linolenic to EPA have been exaggerated. Years: build up to 1997.

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Correspondence to A. Stewart Truswell .

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Truswell, A.S. (2010). Linoleic Acid is Protective. In: Cholesterol and Beyond. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-8875-8_25

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