Abstract
The dietary fibre hypothesis attracted popular and research attention in the 1970s. Trowell expected that wheat fibre (wholemeal bread) would lower plasma cholesterol. In controlled human experiments it did not, but subsequently viscous types of dietary fibre did lower plasma cholesterol – pectin, guar gum, oat bran and psyllium. The mechanism appears to be entrapment of bile acids in the terminal ileum, preventing their reabsorption, hence a negative sterol balance.
There is also more recent epidemiological evidence that high intakes of whole grain cereals are negatively associated with CHD (mechanism unclear) and so are high intakes of vegetables and fruits. Years 1976 onwards.
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Truswell, A.S. (2010). Dietary Fibre. In: Cholesterol and Beyond. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-8875-8_15
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DOI: https://doi.org/10.1007/978-90-481-8875-8_15
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Publisher Name: Springer, Dordrecht
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Online ISBN: 978-90-481-8875-8
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