Abstract
There are significant changes in the cardiovascular system during pregnancy (Blanchard and Shabetai, 2004; Monga, 2004; McAnulty et al., 2008). The total blood volume increases steadily during the first trimester and it is increased by almost 50% by the 30th gestational week without any further change in the last weeks of pregnancy. Between 8th and 32nd gestational week, plasma volume increases more intensively (up to 45%) than red blood cell mass (25%). This explains the common “physiologic” anemia of pregnancy, which without iron supplementation may result in low hematocrit (about 33 ml/dL) and hemoglobin (11 g/dL) values.
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Ács, N., Bánhidy, F., Czeizel, A.E. (2010). Diseases of the Circulatory System. In: Ács, N., Bánhidy, F., Czeizel, A. (eds) Congenital Abnormalities and Preterm Birth Related to Maternal Illnesses During Pregnancy. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-8620-4_10
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