Abstract
To rationally design biological networks at the molecular interaction level, computer-aided design (CAD) is a promising technology, which is based on analogy to engineering technology. CADLIVE (Computer-Aided Design of LIVing systEms) is a comprehensive software suit that consists of multiple modules: a GUI-supported network designer, a database, an automatic layout application, and a dynamic simulator. The most advantageous feature is that the employed regulator-reaction equations connect these applications directly. Once a biochemical network map is provided, CADLIVE efficiently analyzes its static and dynamic features. It is one of the most advanced and integrative bio-simulators.
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Acknowledgements
This work was supported by KAKENHI (Grant-in-Aid for Scientific Research) on Priority Areas “Systems Genomics” from the Ministry of Education, Culture, Sports, Science and Technology of Japan and partially by KAKENHI (Grant-in-Aid for Scientific Research (B), 2006, 18300098).
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Kurata, H. (2010). Computer Aided Rational Design of Biochemical Systems. In: Kamihira, M., Katakura, Y., Ito, A. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3892-0_2
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DOI: https://doi.org/10.1007/978-90-481-3892-0_2
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