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Gene Technology in Forensic Sciences

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Book cover Molecular Diagnostics: Promises and Possibilities

Abstract

Recombinant DNA technology can provide novel and powerful methods for forensic science application. Human genomic DNA can be analyzed directly for individual identification and paternity testing on the basis of polymorphism in its sequence. Restriction fragment length polymorphism (RFLP) testing, STR (microsatellite) and mitochondrial DNA analysis (mtDNA) is suitable for examination of the forensic biological samples (bloodstains, hairs, seminal stains, bones, tooth). Using a combination of single locus probe (SLP) that varies highly among individuals, a DNA fingerprint or profile can be made. Mitochondrial DNA RFLPs may also suggest the characteristics of the human races.

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Debnath, M., Prasad, G.B., Bisen, P.S. (2010). Gene Technology in Forensic Sciences. In: Molecular Diagnostics: Promises and Possibilities. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3261-4_27

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