Skip to main content
SpringerLink
Log in

Salivary Gland Tumors: Preoperative Tissue Characterization with Apparent Diffusion Coefficient Mapping

  • Chapter
  • First Online:
Methods of Cancer Diagnosis, Therapy, and Prognosis

Part of the book series: Methods of Cancer Diagnosis, Therapy and Prognosis ((HAYAT,volume 7))

Abstract

Diffusion-weighted imaging is a magnetic resonance (MR) imaging technology used to measure the Brownian motion of water molecules in tissues. The technique, therefore, is expected to contribute to the evaluation of diseased states of the organs and tissues. However, due to its inherent susceptibility to motion artifacts, the clinical application of the imaging has been limited to the brain (Thoeny and De Keyzer 2007). Due to several technical innovations (particularly faster imaging techniques), diffusion-weighted imaging can now be applied to extracranial organs for imaging diagnosis (Takahara et al. 2004). Here, we describe tissue characterization of salivary gland tumors by using diffusion-weighted imaging with a surface coil. Using this technique, clinicians can know the 2-dimensional (2D) distribution of various tissues in salivary gland tumors before surgery; this information may help predict tumor characteristics, including its benign or malignant state.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 269.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 349.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Barnes L, Everson JW, Reichar P, Sidransky D (2005) Pathology and genetics of head and neck tumors; World Health Organization Classification of Tumours. IARC Press, Lyon

    Google Scholar 

  • Brown R (1828) A brief account of microscopipcal observations made in the months of June, July, and August, 1827, on the particles contained in the pollen of plants; and on the general existence of active molecules in organic and inorganic bodies. Philos Mag 4:161-173

    Google Scholar 

  • Callaghan PT, Macgowan D, Packer KJ, Zelaya FO (1990) High resolution q-space imaging in porous structures. J Magn Reson 90:177-182

    Google Scholar 

  • Eida S, Sumi M, Sakihama N, Takahashi H, Nakamura T (2007) Apparent diffusion coefficient mapping of salivary gland tumors: prediction of the benignancy and malignancy. AJNR Am J Neuroradiol 28:116-121

    PubMed  CAS  Google Scholar 

  • Einstein A (1905) Ãœber die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen. Ann Phys (Leipzig) 17:549-560

    CAS  Google Scholar 

  • Farzaneh F, Riederer SJ, Pelc NJ (1990) Analysis of T2 limitations and off-resonance effects on spatial resolution and artifacts in echo-planar imaging. Magn Reson Med 14:123-139

    Article  PubMed  CAS  Google Scholar 

  • Ikeda M, Motoori K, Hanazawa T, Nagai Y, Yamamoto S, Ueda T, Funatsu H, Ito H (2004) Warthin tumor of the parotid gland: diagnostic value of MR imaging with histopathologic correlation. AJNR Am J Neuroradiol 25:1256-1262

    PubMed  Google Scholar 

  • Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161:401-407

    PubMed  Google Scholar 

  • Kurihara Y, Yakushiji YK, Tani I, Nakajima Y, Van Cauteren M (2002) Coil sensitivity encoding in MR imaging: advantages and disadvantages in clinical practice. AJR Am J Roentgenol 178:1087-1091

    PubMed  Google Scholar 

  • Lyng H, Haraldseth O, Rofstad EK (2000) Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging. Magn Reson Med 43:828-836

    Article  PubMed  CAS  Google Scholar 

  • Moseley ME, Cohen Y, Mintorovitch J, Kurcharczyk J, Chileuitt L, Shimizu H, Kurcharczyk J, Wendland MF, Weintein PR (1990) Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 14:330-346

    Article  PubMed  CAS  Google Scholar 

  • Motoori K, Iida Y, Nagai Y, Yamamoto S, Ueda T, Funatsu H, Ito H, Okamoto Y (2005) MR imaging of salivary duct carcinoma. AJNR Am J Neuroradiol 26:1201-1206

    PubMed  Google Scholar 

  • Motoori K, Yamamoto S, Ueda T, Nakano K, Muto T, Nagai Y, Ikeda M, Funatsu H, Ito H (2004) Inter- and intratumoral variability in magnetic resonance imaging of pleomorphic adenoma. J Compt Assist Tomogr 28:233-246

    Article  Google Scholar 

  • Nakamura T, Sumi M (2007) Nodal imaging in the neck: recent advances in US, CT and MR imaging of metastatic nodes. Eur Radiol 17:1235-1241

    Article  PubMed  Google Scholar 

  • Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) SENSE: sensitivity encoding for fast MRI. Magn Reson Med 42:952-962

    Article  PubMed  CAS  Google Scholar 

  • Sinha S, Lucas-Quesada FA, Sinha U, DeBruhl N, Bassett LW (2002) In vivo diffusion-weighted MRI of the breast: potential for lesion characterization. J Magn Reson Imaging 15:693-704

    Article  PubMed  Google Scholar 

  • Sumi M, Ichikawa Y, Nakamura T (2007) Diagnostic ability of apparent diffusion coefficients for lymphomas and carcinomas in the pharynx. Eur Radiol 17:2631-2637

    Article  PubMed  Google Scholar 

  • Sumi M, Izumi M, Yonetsu K, Nakamura T (1999) Sublingual gland: MR features of normal and diseased states. AJR Am J Roentgenol 172:717-722

    PubMed  CAS  Google Scholar 

  • Sumi M, Sakihama N, Sumi T, Morikawa M, Uetani M, Kabasawa H, Shigeno K, Hayashi K, Takahashi H, Nakamura T (2003) Discrimination of metastatic cervical lymph nodes with diffusion-weighted MR imaging in patients with head and neck cancer. AJNR Am J Neuroradiol 24:1627-1634

    PubMed  Google Scholar 

  • Sumi M, Takagi Y, Uetani M, Morikawa M, Hayashi K, Kabasawa H, Aikawa K, Nakamura T (2002) Diffusion-weighted echoplanar MR imaging of the salivary glands. AJR Am J Roentgenol 178:959-965

    PubMed  Google Scholar 

  • Takahara T, Imai Y, Yamashita T, Yasuda S, Nasu S, Van Cauteren M (2004) Diffusion weighted whole body imaging with background body signal suppressed (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med 22:275-282

    PubMed  Google Scholar 

  • Taouli B, Vilgrain V, Dumont E, Daire JL, Fan B, Menu Y (2003) Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. Radiology 226:71-78

    Article  PubMed  Google Scholar 

  • Thoeny HC (2007) Imaging of salivary gland tumours. Cancer Imaging 7:52-62

    Article  PubMed  Google Scholar 

  • Thoeny HC, De Keyzer F (2007) Extracranial applications of diffusion-weighted magnetic resonance imaging. Eur Radiol 17:1385-1393

    Article  PubMed  Google Scholar 

  • Thoeny HC, De Keyzer F, Boesch C, Hermans R (2004) Diffusion-weighted imaging of the parotid gland: influence of the choice of b-­values on the apparent diffusion coefficient value. J Magn Reson Imaging 20:786-790

    Article  PubMed  Google Scholar 

  • Thoeny HC, De Keyzer F, Claus FG, Sunaert S, Hermans R (2005) Gustatory stimulation changes the apparent diffusion coefficient of salivary glands: initial experience. Radiology 235:629-634

    Article  PubMed  Google Scholar 

  • van Gelderen P, de Vleeschouwer MHM, DesPres D, Pekar J, van Zijl PCM, Moonen CTW (1994) Water diffusion and acute stroke. Magn Res Med 31:154-163

    Article  Google Scholar 

  • Zhang L, Murata Y, Ishida R, Ohashi I, Yoshimura R, Shibuya H (2001) Functional evaluation with intravoxel incoherent motion echo-planar MRI in irradiated salivary glands: a correlative study with salivary gland scintigraphy. J Magn Reson Imaging 14:223-229

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology and Cancer Biology, Nagasaki University School of Dentistry, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan

    Takashi Nakamura, Misa Sumi & Marc Van Cauteren

Authors
  1. Takashi Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Misa Sumi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marc Van Cauteren
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Takashi Nakamura .

Editor information

Editors and Affiliations

  1. Dept. Biological Sciences, Kean University, Union, 07083, USA

    M. A. Hayat

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media B.V.

About this chapter

Cite this chapter

Nakamura, T., Sumi, M., Van Cauteren, M. (2010). Salivary Gland Tumors: Preoperative Tissue Characterization with Apparent Diffusion Coefficient Mapping. In: Hayat, M. (eds) Methods of Cancer Diagnosis, Therapy, and Prognosis. Methods of Cancer Diagnosis, Therapy and Prognosis, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3186-0_18

Download citation

  • DOI: https://doi.org/10.1007/978-90-481-3186-0_18

  • Published:

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-3185-3

  • Online ISBN: 978-90-481-3186-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation