Abstract
Bio-nanorobotics is a new and rapidly growing interdisciplinary field addressing the assembly, construction and utilization of biomolecular devices based on nanoscale principles and/or dimensions. A key application is for medical target identification in therapeutical diagnosis, medical therapies and minimally invasive surgery (MIS) (Calvacanti et al. in Nanotechnology 19:1–15, 2008; Requicha in Proc. IEEE Sens. 91(11):1922–1933, 2003; Hogg and Kuekes in Nanomed. Nanotechnol. Biol. Med. 2(4):239–247, 2006) Modern engineering actuation techniques inspired by nature have been successfully implemented in microrobots evolving in fluidic environments using external electromagnetic fields (Yesin et al. in Int. J. Rob. Res. 25(5–6):527–536, 2006; Mathieu et al. in IEEE Trans. Biomed. Eng. 53(2):292–299, 2006; Behkam and Sitti in J. Dyn. Syst. Meas. Control 128:36–43, 2006). On contrary, biological approach shows that flagellated propulsion mechanisms of bacteria (Martel et al. in Appl. Phys. Lett. 89:233804, 2006), peptide based nanoGripper (Sharma et al. in Int. J. Rob. Res., 2009) or magnetic stereotaxis systems (Steager et al. in Appl. Phys. Lett. 90:263901, 2006) represent a fertile territory for untethered nanoscale machines without the need of external hardware for actuation. Developing nanorobots out of proteins elements requires the merging of two fields of research approaches: the inspiration by nature and biology (“biomimetics”) and the inspiration by large scale machines and the traditional machine theory (“machine nanomimetics”).
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Hamdi, M., Ferreira, A. (2011). Design and Computational Analysis of Bio-Nanorobotic Structures. In: Design, Modeling and Characterization of Bio-Nanorobotic Systems. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3180-8_3
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DOI: https://doi.org/10.1007/978-90-481-3180-8_3
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