• Thomas DittmarEmail author
  • Kurt S. Zänker


Within the past years our knowledge about stem cell biology in health and disease has changed dramatically. What rather sounded like Science Fiction 10–15 years ago, namely that e.g., stem cells from bone marrow or from adipose tissues can be used for regenerative medical approaches, or that it is possible to create donor specific stem cells (so-called induced pluripotent stem cells (iPS cells), exhibiting embryonic stem cell (ESC) properties) simply by transducing 2–4 transcription factors, has now become reality. Likewise, the knowledge that cancer tissues are hierarchically organized like normal tissues, namely comprising of a small amount of tumorigenic cancer stem cells (CSCs) and a huge mass of non-tumorigenic cancer cells will play a crucial role in the development of novel anti-cancer strategies.


Stem Cell Adult Stem Cell Stem Cell Biology Stem Cell State Bone Marrow Reconstitution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  1. 1.Institute of ImmunologyFaculty of Medicine, Witten/Herdecke UniversityWittenGermany

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