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N-Heterocyclic Carbene Complexes in Cyclisation Reactions

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N-Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis

Part of the book series: Catalysis by Metal Complexes ((CMCO,volume 32))

  • 2010 Accesses

Abstract

Cycloaddition reactions hold a prominent place in the arsenal of synthetic methods currently available to organic chemists. Although some cycloadditions can be promoted simply by heat, light, Lewis acids, high pressure or sonication, many cycloadditions require the use of a transition metal to catalyse the reaction. Transition metal catalysed cycloaddition is an attractive approach as it provides an opportunity to obtain regio- and/or enantio-pure cyclic products. The use of N-heterocyclic carbenes (NHCs) as ligands is a rapidly expanding field. As will be discussed in this chapter, these ligands have been used in conjunction with several metals in the synthesis of a wide range of carbocycles and heterocycles through cycloaddition reactions.

An erratum to this chapter can be found at http://dx.doi.org/10.1007/978-90-481-2866-2_15

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Authors and Affiliations

  1. Department of Chemistry, University of Utah, Salt Lake City, Utah, 84112-0850, USA

    Janis Louie

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  1. Janis Louie
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Correspondence to Janis Louie .

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Editors and Affiliations

  1. School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, Fife, KY16 9ST, United Kingdom

    Catherine S.J. Cazin

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Louie, J. (2010). N-Heterocyclic Carbene Complexes in Cyclisation Reactions. In: Cazin, C. (eds) N-Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis. Catalysis by Metal Complexes, vol 32. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2866-2_5

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