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Fatty Acid Biosynthesis in Plants — Metabolic Pathways, Structure and Organization

  • Chapter
Lipids in Photosynthesis

Part of the book series: Advances in Photosynthesis and Respiration ((AIPH,volume 30))

Summary

Progress in the elucidation of metabolic pathways for fatty acid and triacylglycerol biosynthesis in plants is reviewed, together with evidence for gene function. Research in this area is being driven by the importance of storage lipids as potential new raw materials to replace petrochemicals. Significant advances have been made in the structural analysis of a number of the soluble enzymes in these pathways but progress still has to be made on membrane-bound enzymes. Many of the enzymes of triacylglycerol biosynthesis have been identified but the relative importance of the acyl-CoA dependent and independent pathways remains to be determined. The role of particular isoenzymes in specific triacylglycerol assembly remains a major challenge together with determining higher orders of enzyme interaction and metabolic channeling.

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Abbreviations

ACCase:

Acetyl-CoA carboxylase

ACP:

Acyl-carrier protein

CoA:

Coenzyme A

DGAT:

Diacylglycerol acyltransferase

FAS:

Fatty acid synthase

GPAT:

Glycerol-3-phosphate acyltransferase

PDAT:

Phospholipid: diacylglycerol acyltransferase

LPAT:

1-Acyl sn-glycerol-3-phosphate acyltransferase

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Acknowledgments

The authors wish to thank the Biological and Biotechnology Research Council for supporting work in the Durham and Sheffield laboratories over the years. Specific acknowledgement is given by Antoni R. Slabas and Adrian P. Brown for support from the LINK “Renewable Raw Materials” programme for the work on Ricinus.

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Authors and Affiliations

  1. School of Biological and Biomedical Sciences, University of Durham, South Road, Durham, DH1 3LE, UK

    Adrian P. Brown & Antoni R. Slabas

  2. Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, University of Sheffield, S10 2TN, Sheffield, UK

    John B. Rafferty

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  1. Adrian P. Brown
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  2. Antoni R. Slabas
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Correspondence to Antoni R. Slabas .

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  1. Department of Life Sciences, Graduate School of Arts and Science, University of Tokyo, Japan

    Hajime Wada

  2. National Institute for Basic Biology, Okazaki, Japan

    Norio Murata

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Brown, A.P., Slabas, A.R., Rafferty, J.B. (2009). Fatty Acid Biosynthesis in Plants — Metabolic Pathways, Structure and Organization. In: Wada, H., Murata, N. (eds) Lipids in Photosynthesis. Advances in Photosynthesis and Respiration, vol 30. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2863-1_2

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