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Supramolecular Chemistry pp 113–151Cite as

Supramolecular Enzyme Mimics

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Abstract

The reliance of enzymes on the weak reversible interactions central to supramolecular chemistry is discussed. Specific examples are described in more detail (haemoglobin, myoglobin, cytochromes, catalytic pro- and antioxidants, photosystems, copper and zinc containing enzymes) together with their supramolecular analogues. Artificial systems for photosynthesis, cyclodextrins as artificial enzyme supports, and model enzymes that do not require metals are considered. Other non-biological systems that rely on reversible complementary interactions (molecular imprinted polymers, combinatorial polymers, and dynamic combinatorial libraries) are described. De novo design and evolutionary development of enzymes is discussed.

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Authors and Affiliations

  1. School of Pharmacy and Biomolecular Sciences, University of Brighton, Huxley Bldg, Lewes Road, BN2 4GJ, Brighton, UK

    Dr. Peter J. Cragg

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  1. Dr. Peter J. Cragg
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Correspondence to Peter J. Cragg .

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Cragg, P.J. (2010). Supramolecular Enzyme Mimics. In: Supramolecular Chemistry. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2582-1_4

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