Skip to main content
SpringerLink
Log in

Voeding bij galblaas- en leveraandoeningen

December 2017

  • Chapter
  • First Online:
Informatorium voor Voeding en Diëtetiek

  • 1414 Accesses

Samenvatting

De galblaas is de opslagplaats voor de galvloeistof die in de lever wordt gemaakt. Galstenen komen vaker voor bij mensen met overgewicht en/of een verkeerde leefstijl. Het aanpassen van leefstijlfactoren met dieetmaatregelen en een actieve leefstijl kunnen bijdragen aan de preventie van galstenen. De lever is een belangrijk orgaan voor de stofwisseling van koolhydraten, eiwitten en vetten. Bovendien zorgt de lever voor afbraak van schadelijke stoffen, zoals alcohol en medicatie. Chronische ontsteking van de lever kan uiteindelijk leiden tot levercirrose. Levercirrose geeft aanvankelijk weinig klachten, maar hoe verder de leverfunctie achteruitgaat, des te meer klachten en complicaties er ontstaan. Leverkanker is een belangrijke doodsoorzaak onder patiënten met levercirrose. In het eindstadium van levercirrose is levertransplantatie soms de enige behandeling. Ondervoeding en verlies van spiermassa, ofwel sarcopenie, komen bij 40–80 % van de patiënten met levercirrose voor. Er zijn verschillende methoden om de voedingstoestand te bepalen. Dieetmaatregelen dragen onder andere bij aan verbeteren van de leverfunctie en het voorkomen van complicaties. Er is verhoogd risico op vitamine- en mineralendeficiënties, zodat vaak suppletie nodig is. Het aantal patiënten met leververvetting stijgt evenredig met de toename van mensen met obesitas en het metabool syndroom. Voedings- en beweegmaatregelen kunnen de hoeveelheid vet in de lever verlagen.

Met dank aan J.H.M. Brouns, diëtist maag-darm-leverziekten UMC Maastricht, en prof. B. van Hoek, MDL-arts LUMC, Leiden

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 19.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 27.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatuur

  • Abdelsayed, G. G. (2015). Diets in encephalopathy. Clinical Liver Disease, 19, 497–505.

    Article  Google Scholar 

  • Beery, R. M. M., Vaziri, H., & Forouhar, F. (2014). Primary biliary cirrhosis and primary sclerosing cholangitis: A review featuring a women’s health perspective. Journal of Clinical and Translational Hepatology, 2(4), 266–284.

    Google Scholar 

  • Boonstra, K., Weersma, R. K., Erpecum, K. J. van, et al. (2013). Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis. Hepatology, 58(6), 20145–20155.

    Article  Google Scholar 

  • Bosma, J. W., Meyel, J. J. M. van, & Sieert, E. (2010). Stand van zaken. Het hepatorenaalsyndroom; pathofysiologie en behandeling. Nederlands Tijdschrift voor Geneeskunde, 154, A1355.

    Google Scholar 

  • Chadalavada, R., Biyyani, R. S. S., Maxwell, J., et al. (2010). Nutrition in hepatic encephalopathy. Nutrition in Clinical Practice, 25(3), 257–264.

    Google Scholar 

  • Cnossen, W. R., & Drenth, J. P. H. (2014). Polycystic liver disease: An overview of pathogenesis, clinical manifestations and management. Orphanet Journal of Rare Diseases, 9, 69. doi:10.1186/1750-1172-9-69.

    Article  PubMed  PubMed Central  Google Scholar 

  • Doorn, G. M. van (2011). Voedingsadvies bij HFE-hemochromatose. Rapport 279 Departement Humane Voeding. Wageningen: Wageningen University.

    Google Scholar 

  • EASL (2016). Clinical practice guidelines on the prevention, diagnosis and treatment of gallstones. Journal of Hepatology, 65, 146–181.

    Google Scholar 

  • EASL-EORTC (2012). Clinical practice guidelines: Management of hepatocellular carcinoma. Journal of Hepatology, 56, 908–943.

    Google Scholar 

  • Fernandes, S. A., Mattos A. A. de, Tovo, C. V., et al. (2016). Nutritional evaluation in cirrhosis: Emphasis on the phase angle. World Journal of Hepatology, 8(29), 1205–1211.

    Google Scholar 

  • Ge, Ph. S., & Runyon, B. A. (2016). Treatment of patients with cirrhosis. New England Journal of Medicine, 375, 767–777.

    Article  Google Scholar 

  • Gerven, N. M. van, Verwer, B. J., Witte, B. I., et al. (2014). Epidemiology and clinical characteristics of autoimmune hepatitis in the Netherlands. Scandinavian Journal of Gastroenterology, 49(10), 1245–1254. doi:10.3109/00365521.2014.946083. Epub 2014 Aug 15.

  • Gezondheidsraad (2015). Richtlijnen goede voeding 2015, publicatienr. 2015/24. Den Haag: Gezondheidsraad.

    Google Scholar 

  • Gluud, L. L., Dam, G., Les, I., Córdoba, J., Marchesini, G., et al. (2015). Branched-chain amino acids for people with hepatic encephalopathy. Cochrane Database of Systematic Reviews, 9, CD001939. doi:10.1002/14651858.CD001939.pub3.

  • Gupta, V., Mah, X. J., Garcia, M. C., et al. (2015). Oily fish, coffee and walnuts: Dietary treatment for nonalcoholic fatty liver disease. World Journal of Gastroenterology, 21(37), 10621–10635. doi:10.3748/wjg.v21.i37.10621.

  • Hannah, W. N., Jr., & Harrison, S. A. (2016). Lifestyle and dietary interventions in the management of nonalcoholic fatty liver disease. Digestive Diseases and Sciences, 61(5), 1365–1374.

    Article  CAS  PubMed  Google Scholar 

  • Hörner, V. D., Avery, A., & Stow, R. (2017). The effects of probiotics and symbiotics on risk factors for hepatic encephalopathy: A systematic review. Journal of Clinical Gastroenterology, 51(4), 312–323.

    Article  Google Scholar 

  • Integraal Kankercentrum Nederland (IKNL) (2013). Richtlijn galweg- en galblaascarcinoom. Utrecht: IKNL.

    Google Scholar 

  • Iruzubieta, P., Teran, A., Crespo, J., et al. (2014). Vitamin D deficiency in chronic liver disease. World Journal of Hepatology, 6(12), 901–915.

    Google Scholar 

  • Janssen, L. A. H., Drenth, J., & Hoek, B. van (2009) Leverziekten. Houten: Bohn Stafleu van Loghum.

    Book  Google Scholar 

  • Johnson, T. M., Overgard, E. B., Cohen, A. E., et al. (2013). Nutrition assessment and management in advanced liver disease. Nutrition in Clinical Practice, 28(1), 15–29.

    Google Scholar 

  • Kim, H. Y., & Jang, J. Won. (2015). Sarcopenia in the prognosis of cirrhosis: Going beyond the MELD-score. World Journal of Gastroenterology, 21(25), 7637–7647.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kirpich, I. A., Marsana, L. S., & McClain, C. J. (2015). Gut-liver axis, nutrition, and non-alcoholic fatty liver disease. Clinical Biochemistry, 48(13–14), 923–930.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Krol, C. G., Dekkers, O. F., & Kroon, H. M. (2014). No association between BMD and prevalent vertebral fractures in liver transplant recipients at time of screening before transplantation. Journal of Clinical Endocrinology and Metabolism, 99(10), 3677–3685.

    Article  CAS  PubMed  Google Scholar 

  • Kuiken, S. D., Delden, O. M. van, Richel, D. J., et al. (2009). De behandeling van het hepatocellulair carcinoom. Nieuwe ontwikkelingen. Nederlands Tijdschrift voor Geneeskunde, 153, B151.

    Google Scholar 

  • Kuiper, E. M. M., Ouden-Muller, J. W. den, & Buuren, H. R. van (2009). Stand van zaken primaire biliaire cirrose. Nederlands Tijdschrift voor Geneeskunde, 153, A483.

    PubMed  Google Scholar 

  • Lander, E. M., Wertheim, B. C., Koch, S. M., et al. (2016). Vegetable protein intake is associated with lower gallbladder disease risk: Findings from the women’s health initiative prospective cohort. Preventive Medicine, 88, 20–26.

    Google Scholar 

  • Mandair, D. S., Rossi, R. E., & Pericleous, M. (2014). The impact of diet and nutrition in the prevention and progression of hepatocellular carcinoma. Expert Review of Gastroenterology & Hepatology, 8(4), 369–382.

    Article  CAS  Google Scholar 

  • Modi, R. M., Patel, N., Metwally, S. N., et al. (2016). Outcomes of liver transplantation on patients with hepatorenal syndrome. World Journal of Hepatology, 8(24), 999–1011.

    Google Scholar 

  • Montano-Loza, A. J., Angulo, P., Meza-Junco, J., et al. (2016). Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis. Journal of Cachexia, Sarcopenia and Muscle, 7, 126–135.

    Google Scholar 

  • Moretti, D., Doorn, G. M. van, Swinkels, D. W., et al. (2013). Relevance of dietary iron intake and bioavailability in the management of HFE hemochromatosis: A systematic review. American Journal of Clinical Nutrition, 98(2), 468–479. doi:10.3945/ajcn.112.048264.

  • Plauth, M., Cabre, E., Riggio, O., et al. (2006). ESPEN guidelines on enteral nutrition: Liver disease. Clinical Nutrition, 25, 285–294.

    Google Scholar 

  • Portincasa, P., Ciaula, A. di, & Grattagliano, I. (2016). Preventing a mass disease: The case of gallstone disease: Role and competence for family physicians. Korean Journal of Family Medicine, 37, 205–213.

    Article  PubMed  PubMed Central  Google Scholar 

  • Rossi, R. E., Conte, D., & Massironi, S. (2015). Diagnosis and treatment of nutritional deficiencies in alcoholic liver disease: Overview of available evidence and open issues. Digestive and Liver Disease, 47, 819–825.

    Article  PubMed  Google Scholar 

  • Saab, S., Mallam, D., Cox, G. A., et al. (2014). Impact of coffee on liver diseases: A systematic review. Liver International, 34, 495–504.

    Google Scholar 

  • Sachdeva, S., Khan, Z., Ansari, M. A., et al. (2011). Lifestyle and gallstone disease: Scope for primary prevention. Indian Journal of Community Medicine, 36(4), 263–267.

    Google Scholar 

  • Santos, L. A. A., & Romeiro, F. G. (2016). Diagnosis and management of cirrhosis-related osteoporosis. Hindawi publishing corporation. BioMed Research International, Article ID 1423462. http://dx.doi.org/10.1155/2016/1423462.

  • Sinclair, M., Gow, P. J., Grossmann, M., et al. (2016). Review article: Sarcopenia in cirrhosis – aetiology, implications and potential therapeutic interventions. Alimentary Pharmacology & Therapeutics, 43, 765–777.

    Google Scholar 

  • Stachowska, E., Ryterska, K., Maciejewska, D., et al. (2016). Nutritional strategies for the individualized treatment of Non-Alcoholic Fatty Liver Disease (NAFLD) based on the Nutrient-Induced Insulin Output Ratio (NIOR). International Journal of Molecular Science, 17(7), 1192. doi:10.3390/ijms17071192.

  • Szabo, G. (2015). Gut-liver axis in alcoholic liver disease. Gastroenterology, 148(1), 30–36.

    Article  CAS  PubMed  Google Scholar 

  • Tandon, P., Low, G., Mourtzakis, M., et al. (2016). A model to identify sarcopenia in patients with cirrhosis. Clinical Gastroenterology and Hepatology, 14, 1473–1480.

    Google Scholar 

  • Topcu, Y., Tufan, F., & Karan, M. E. (2016). Potential confounders in identification of sarcopenia in cirrhosis. Letters to the editor (vol. 14(11), pag.1671). Turkey: Istanbul. http://dx.doi.org/10.1016/j.cgh.2016.06.022.

  • Tsai, C. J., Leitzmann, M. F., Hu, F. B., et al. (2004). Frequent nut consumption and decreased risk of cholecystectomy in women. American Journal of Clinical Nutrition, 80, 76–81.

    Google Scholar 

  • Tsien, C. D., McCullough, A. J., & Dasarathy, S. (2012). Late evening snack: Exploiting a period of anabolic opportunity in cirrhosis. Journal of Gastroenterology and Hepatology, 27(3), 430–441.

    Article  CAS  PubMed  Google Scholar 

  • Wlazo, N., Beijers, H. J., Schoon, E. J., et al. (2010). High prevalence of diabetes mellitus in patients with liver cirrhosis. Diabetic Medicine, 27(11), 1308–1311.

    Google Scholar 

  • World Cancer Research Fund (WCRF) (2015). Continuous update project: Diet, nutrition, physical activity and gallbladder cancer. London: WCRF.

    Google Scholar 

Websites

Aanbevolen literatuur

  • Campillo, B., et al. (2006). Validation of body mass index for the diagnosis of malnutrition in patients with liver cirrhosis. Gastroentérologie Clinique et Biologique, 30: 1137–1143.

    Google Scholar 

  • Plank, L. D., Gane, E. J., et al. (2008). Nocturnal nutritional supplementation improves total body protein status of patients with liver cirrhosis: A randomized 12 month trial. Hepatology, 48(2), 557–566.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. LUMC, Leiden, Nederland

    A. S. Donker (diëtist)

Authors
  1. A. S. Donker
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Almere, The Netherlands

    Majorie Former

  2. Delft, The Netherlands

    Gerdie van Asseldonk

  3. Garrelsweer, The Netherlands

    Jacqueline Drenth

  4. Den Hoorn, The Netherlands

    Caroelien Schuurman

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Bohn Stafleu van Loghum, onderdeel van Springer Media B.V.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Donker, A.S. (2017). Voeding bij galblaas- en leveraandoeningen. In: Former, M., van Asseldonk, G., Drenth, J., Schuurman, C. (eds) Informatorium voor Voeding en Diëtetiek. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-1987-9_3

Download citation

  • DOI: https://doi.org/10.1007/978-90-368-1987-9_3

  • Published:

  • Publisher Name: Bohn Stafleu van Loghum, Houten

  • Print ISBN: 978-90-368-1986-2

  • Online ISBN: 978-90-368-1987-9

  • eBook Packages: Dutch language eBook collection

Publish with us

Policies and ethics

Search

Navigation