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Diepe hersenstimulatie bij het syndroom van Gilles de la Tourette

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Handboek diepe hersenstimulatie bij neurologische en psychiatrische aandoeningen

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Samenvatting

Het syndroom van Gilles de la Tourette (‘Gilles de la Tourette Syndrome’, GTS) komt voor bij gemiddeld 1 % van de jongeren tussen de 5 en 18 jaar en wordt gekenmerkt door chronische motorische en vocale tics. De klachten kunnen doorgaans goed behandeld worden met bepaalde vormen van psychotherapie en/of medicatie. Bij ernstige en therapieresistente klachten kan behandeling met diepe hersenstimulatie ('deep brain stimulation', DBS) overwogen worden. Uit gepubliceerde ziektegevallen en een heel beperkt aantal onderzoeken wordt duidelijk dat DBS een veilige en effectieve behandeling kan zijn bij een geselecteerde groep patiënten. Bij sommige bewegingsstoornissen is DBS een reguliere behandelmethode, maar behandeling van therapieresistente GTS met diepe hersenstimulatie moet gezien worden als een ‘last resort’ behandeling, die alleen in gespecialiseerde centra kan plaatsvinden. Verder onderzoek moet helpen om meer inzicht te verkrijgen in selectie van stimulatietargets, stimulatieparameters en de effectiviteit van deze behandeling.

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Literatuur

  1. Robertson MM. Tourette syndrome, associated conditions and the complexities of treatment. Brain. 2000;123:425–62.

    Article  PubMed  Google Scholar 

  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5). 5th ed. Washington: American Psychiatric Association; 2013.

    Book  Google Scholar 

  3. Müller-Vahl KR, Riemann L, Bokemeyer S. Tourette patients’ misbelief of a tic rebound is due to overall difficulties in reliable tic rating. J Psychosom Res. 2014;76:472–6.

    Article  PubMed  Google Scholar 

  4. Verdellen CW, Hoogduin CA, Keijsers GP. Tic suppression in the treatment of Tourette’s syndrome with exposure therapy: the rebound phenomenon reconsidered. Mov Disord. 2007;22:1601–6.

    Article  PubMed  Google Scholar 

  5. Robertson MM. The prevalence and epidemiology of Gilles de la Tourette syndrome. Part 1: the epidemiological and prevalence studies. J Psychosom Res. 2008;65:461–72.

    Article  PubMed  Google Scholar 

  6. Robertson MM, Banjeree S, Eapen V, Fox-Hiley P. Obsessive compulsive behaviour and depressive symptoms in young people with Tourette syndrome. A controlled study. Eur Child Adolesc Psychiatry. 2002;11:261–5.

    Article  PubMed  Google Scholar 

  7. Verdellen C, Griendt J van de, Hartmann A, Murphy T and the ESSTS Guidelines Group. European clinical guidelines for Tourette syndrome and other tic disorders. Part III: behavioural and psychosocial interventions. Eur Child Adolesc Psychiatry 2011;20:197–207.

    Google Scholar 

  8. Roessner V, Plessen KJ, Rothenberger A, Ludolph AG, Rizzo R, Skov L, et al., and The ESSTS Guidelines Group. European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. Eur Child Adolesc Psychiatry. 2011;20:173–96.

    Google Scholar 

  9. Hallett M. Tourette syndrome: update. Brain Dev. 2015;37:651–5.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Mink JW. Basal ganglia dysfunction in Tourette’s syndrome: a new hypothesis. Pediatr Neurol. 2001;25:190–8.

    Article  CAS  PubMed  Google Scholar 

  11. Mink JW, Thach WT. Basal ganglia intrinsic circuits and their role in behavior. Curr Opin Neurobiol. 1993;3:950–7.

    Article  CAS  PubMed  Google Scholar 

  12. Cunha CD, Boschen SL, Gomez-AA, et al. Toward sophisticated basal ganglia neuromodulation: review on basal ganglia deep brain stimulation. Neurosci Biobehav Rev. 2015;58:186–210.

    Google Scholar 

  13. Schrock LE, Mink JW, Woods DW, et al. Tourette Syndrome Association International Deep Brain Stimulation (DBS) Database and Registry Study Group. Mov Disord. 2014;30:448–71.

    Article  PubMed  Google Scholar 

  14. Temel Y, Visser-Vandewalle V. Surgery in Tourette syndrome. Mov Disord. 2004;19:3–14.

    Article  PubMed  Google Scholar 

  15. Vandewalle V, Linden C van der, Groenewegen HJ, Caemaert J. Stereotactic treatment of Gilles de la Tourette syndrome by high frequency stimulation of thalamus. Lancet 1999;353:724.

    Google Scholar 

  16. Maciunas R, Maddux B, Riley D, et al. Prospective randomized double-blind trial of bilateral thalamic deep brain stimulation in adults with Tourette syndrome. J Neurosurg. 2007;107:1004–14.

    Article  PubMed  Google Scholar 

  17. Ackermans L, Duits A, Linden C van der, et al. Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome. Brain. 2011;134:832–44.

    Google Scholar 

  18. Welter M, Mallet L, Houeto J, et al. Internal pallidal and thalamic stimulation in patients with Tourette syndrome. Arch Neurol. 2008;65:952–7.

    Article  PubMed  Google Scholar 

  19. Motlagh M, Smith M, Landeros-Weisenberger A, et al. Lessons learned from open-label deep brain stimulation for Tourette Syndrome: Eight cases over 7 years. Tremor and Other Hyperkinetic Movements. 2013;3(1):tre-03-170-4428-1 (http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879075).

  20. Visser-Vandewalle V, Temel Y, Boon P, et al. Chronic bilateral thalamic stimulation, a new therapeutic approach in intractable Tourette syndrome: a report of three cases. J Neurosurg. 2003;99:1094–100.

    Article  PubMed  Google Scholar 

  21. Hassler R, Dieckmann G. Traitement stéréotaxique des tics et cris inarticules ou coprolaliques considérés comme phénomène d’obsession mortice au cours de la maladie de Gilles de la Tourette. Rev Neurol. 1970;123:89–100.

    CAS  PubMed  Google Scholar 

  22. Linden C van der, Colle H, Vandewalle V, et al. Succesful treatment of tics with bilateral internal pallidum stimulation in a 27-year old male patient with Gilles de la Tourette syndrome. Mov Disord. 2002;17:341.

    Google Scholar 

  23. Saleh C, Gonzalez V, Cif L, Coubes P. Deep brain stimulation of the globus pallidus internus and Gilles de la Tourette syndrome: Toward multiple networks modulation. Surg Neurol Int. 2012;3S:127–42.

    Google Scholar 

  24. Ackermans L, Temel Y, Cath D, Linden C van der, Bruggeman R, Kleijer M, et al. Deep brain stimulation in Tourette’s syndrome: two targets? Mov Disord. 2006;21:709–13.

    Google Scholar 

  25. Houeto JL, Karachi C, Mallet L, Pillon B, Yelnik J, Mesnage V, et al. Tourette’s syndrome and deep brain stimulation. J Neurol Neurosurg Psychiatry. 2005;76:992–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Massano J, Sousa C, Foltynie T, Zrinzo L, Hariz M, Vaz R. Successful pallidal deep brain stimulation in 15-year-old with Tourette syndrome: 2-year follow-up. J Neurol. 2013;260:2417–9.

    Article  PubMed  Google Scholar 

  27. Martinez-Fernandez R, Zrinzo L, Aviles-Olmos I, Hariz M, Martinez-Torres I, Joyce E, et al. Deep brain stimulation for Gilles de la Tourette syndrome: a case series targeting subregions of the globus pallidus internus. Mov Disord. 2011;26:1922–30.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Afdeling Neurochirurgie, Maastricht UMC+, Maastricht, The Netherlands

    Linda Ackermans

  2. Afdeling Psychiatrie, Maastricht UMC+, Maastricht, The Netherlands

    Albert Leentjens

Authors
  1. Linda Ackermans
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  2. Albert Leentjens
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Editor information

Editors and Affiliations

  1. Maastricht University Medical Cente Department of Neurosurgery, Maastricht, The Netherlands

    Y. Temel

  2. Dept. Of Psychiatry, Maastricht Univeristy Medical Centre, Maastricht, The Netherlands

    A.F.G. Leentjens

  3. Afd. Neurologie, Amsterdam Medisch Centrum, Amsterdam, The Netherlands

    R.M.A. de Bie

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© 2016 Bohn Stafleu van Loghum

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Ackermans, L., Leentjens, A. (2016). Diepe hersenstimulatie bij het syndroom van Gilles de la Tourette. In: Temel, Y., Leentjens, A., de Bie, R. (eds) Handboek diepe hersenstimulatie bij neurologische en psychiatrische aandoeningen. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-0959-7_16

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  • DOI: https://doi.org/10.1007/978-90-368-0959-7_16

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  • Publisher Name: Bohn Stafleu van Loghum, Houten

  • Print ISBN: 978-90-368-0958-0

  • Online ISBN: 978-90-368-0959-7

  • eBook Packages: Dutch language eBook collection

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