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Handboek diepe hersenstimulatie bij neurologische en psychiatrische aandoeningen pp 85–91Cite as

Programmeren van nucleus subthalamicus diepe hersenstimulatie voor de ziekte van Parkinson

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Samenvatting

Het succes van de behandeling met diepe hersenstimulatie (‘deep brain stimulation’, DBS) wordt onder andere bepaald door de DBS-programmering. De variabelen die geprogrammeerd kunnen worden zijn contactpunten, spanning, stroom, pulsduur en frequentie. Tussen twee en vier weken na implantatie van de DBS-elektroden wordt begonnen met programmeren. Dit begint met het voor elk contactpunt bepalen van de drempelwaarden van stimulatie-intensiteit voor symptoomvermindering en voor bijwerkingen. Het contactpunt met de laagste drempel voor onderdrukken van parkinsonsymptomen en de hoogste drempel voor bijwerkingen wordt aangezet als kathode met de neurostimulator als anode. De stroom/spanning wordt in enkele maanden opgehoogd en de medicatie aangepast. Tussen zes maanden en één jaar na de operatie is bij de meeste patiënten een stabiele fase bereikt, waarbij de instellingen in principe niet veel meer aangepast hoeven te worden. Er zijn verschillende strategieën om problemen met de stimulatie op te lossen.

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Author information

Authors and Affiliations

  1. Afdeling Neurologie, Academisch Medisch Centrum, Amsterdam, The Netherlands

    Rob de Bie

  2. Afdeling Neurologie, Academisch Medisch Centrum/Universiteit van Amsterdam, Amsterdam, The Netherlands

    Miranda Postma

  3. Afdeling Neurologie, Universitair Medisch Centrum, Groningen, The Netherlands

    Elien Steendam-Oldekamp

Authors
  1. Rob de Bie
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  2. Miranda Postma
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  3. Elien Steendam-Oldekamp
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Editor information

Editors and Affiliations

  1. Maastricht University Medical Cente Department of Neurosurgery, Maastricht, The Netherlands

    Y. Temel

  2. Dept. Of Psychiatry, Maastricht Univeristy Medical Centre, Maastricht, The Netherlands

    A.F.G. Leentjens

  3. Afd. Neurologie, Amsterdam Medisch Centrum, Amsterdam, The Netherlands

    R.M.A. de Bie

Copyright information

© 2016 Bohn Stafleu van Loghum

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de Bie, R., Postma, M., Steendam-Oldekamp, E. (2016). Programmeren van nucleus subthalamicus diepe hersenstimulatie voor de ziekte van Parkinson. In: Temel, Y., Leentjens, A., de Bie, R. (eds) Handboek diepe hersenstimulatie bij neurologische en psychiatrische aandoeningen. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-0959-7_11

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  • DOI: https://doi.org/10.1007/978-90-368-0959-7_11

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  • Publisher Name: Bohn Stafleu van Loghum, Houten

  • Print ISBN: 978-90-368-0958-0

  • Online ISBN: 978-90-368-0959-7

  • eBook Packages: Dutch language eBook collection

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