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Oesofaguscarcinoom

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Ontwikkelingen in de oncologie

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Inleiding

Het oesofaguscarcinoom (figuur 24.1) is de op achtst na meest voorkomende en de op zes na dodelijkste kanker in de wereld. Histopathologisch onderscheidt men twee groepen oesofaguscarcinomen: adenocarcinomen en plaveiselcelcarcinomen . Algemeen wordt verondersteld dat adenocarcinomen zich ontwikkelen in een barrettoesofagus . Een barrettoesofagus ontstaat door metaplasie van plaveiselepitheel, dat onder invloed van gastro-oesofageale reflux transformeert tot intestinaal cilinderepitheel (figuur 24.2).

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© 2014 Bohn Stafleu van Loghum

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Kestens, C., van Hillegersberg, R., Siersema, P. (2014). Oesofaguscarcinoom. In: Bröker, L., Eekhof, J. (eds) Ontwikkelingen in de oncologie. Huisarts en Wetenschap. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-0436-3_24

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  • DOI: https://doi.org/10.1007/978-90-368-0436-3_24

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