Inleiding
Bij een congenitaal gecorrigeerde transpositie van de grote arteriën (ccTGA ) is er een normale positie van de atria (situs solitus), maar zijn de atria aangesloten op de ‘verkeerde’ ventrikel (RA op LV en LA op RV), terwijl tevens de aorta uit de RV ontspringt en de art. pulmonalis uit de LV. Er zijn dus discordante AV-connecties en discordante VA-connecties . De circulatie is al tijdens de aanleg van het hart ‘gecorrigeerd’, omdat het bloed op zich goed circuleert: zuurstofarm bloed gaat naar de longen en zuurstofrijk bloed naar het lichaam. ‘Gecorrigeerd’ betekent in dit kader dus niet een operatie! Er is sprake van inversie van de ventrikels waardoor de anatomische RV moet functioneren als systeemventrikel. De LV is de subpulmonale ventrikel . De AV-kleppen volgen de ventrikels, dus de tricuspidalisklep is de systemische AV-klep (figuur 16.1).
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsLiteratuur
Beauchesne LM, Warnes CA, Connolly HM, et al. Outcome of the unoperated adult who presents with congenitally corrected transposition of the great arteries. J Am Coll Cardiol.2002;40:285–290.
Connelly MS, Liu PP, Williams WG, et al. Congenitally corrected transposition of the great arteries in the adult: functional status and complications. J Am Coll Cardiol. 1996; 27: 1238–1243.
Connolly HM, Grogan M, Warnes C. Pregnancy among women with congenitally corrected transposition of great arteries. J Am Coll Cardiol. 1999; 33: 1692–1695.
Dore A, Houde C, Chan KL, et al. Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles. A multicenter, randomized, placebo-controlled clinical trial. Circulation. 2005; 112: 2411–2416.
Graham TP, Bernard YD, Mellen BG, et al. Long-term outcome in congenitally corrected transposition of the great arteries. A multi-institutional study. J Am Coll Cardiol. 2000; 36: 255–261.
Janousek J, Tomek V, Chaloupecky V, et al. Cardiac resynchronisation therapy: a novel adjunct to the treatment and prevention of systemic right ventricular failure. J Am Coll Cardiol. 2004; 44: 1927–1931.
Oliver JM, Gallego P, Gonzalez AE, et al. Comparison of outcomes in adults with congenitally corrected transposition with situs inversus versus situs solitus. Am J Cardiol. 2012; 110(11): 1687–1691.
Piran S, Veldtman G, Siu S, et al. Heart failure and ventricular dysfunction in patients with single or systemic right ventricles. Circulation. 2002; 105: 1189–1194.
Presbitero P, Somerville J, Rabajoli F, et al. Corrected transposition of the great arteries without associated defects in adult patients: clinical profile and follow up. Br Heart J. 1995; 74: 57–59.
Prieto LR, Hordof AJ, Secic M, et al. Progressive tricuspid valve disease in patients with congenitally corrected transposition of the great arteries. Circulation. 1998; 98: 997–1005.
Warnes CA. Transpostion of the great arteries. Circulation. 2006; 114: 1699–2709.
Winlaw DS, McGuirck SP, Balmer C, et al. Intention-to-treat analysis of pulmonary artery banding in conditions with a morphological right ventricle in the systemic circulation with a view to anatomic biventricular repair. Circulation. 2005; 111(4): 405–411.
Winter MM, Bom T van der, Vries LC de, et al. Exercise training improves exervise capacity in adult patients with a systemisc right ventricle: a randomized clinical trial. Eur Heart J. 2012; 33: 1378–1385.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Copyright information
© 2013 Bohn Stafleu van Loghum
About this chapter
Cite this chapter
Roos-Hesselink, J., van Dijk, A. (2013). Congenitaal gecorrigeerde transpositie van de grote arteriën. In: Mulder, B., Pieper, P., Meijboom, F., Hamer, J. (eds) Aangeboren hartafwijkingen bij volwassenen. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-0307-6_16
Download citation
DOI: https://doi.org/10.1007/978-90-368-0307-6_16
Published:
Publisher Name: Bohn Stafleu van Loghum, Houten
Print ISBN: 978-90-368-0306-9
Online ISBN: 978-90-368-0307-6
eBook Packages: Dutch language eBook collection