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Management of Primary Hyperparathyroidism

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Primary, Secondary and Tertiary Hyperparathyroidism

Part of the book series: Updates in Surgery ((UPDATESSURG))

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Abstract

The treatment of symptomatic primary hyperparathyroidism (pHPT) is surgical. Medical therapy has a role for the patient who does not want to, or cannot, be operated on: in these cases hypercalcemia is controlled with cinacalet and the bone mineral density (BMD) is improved with bisphosphonates.

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References

  1. Crouzeix G, Kerlan V (2014) Primary hyperparathyroidism: new concepts, new recommendations. Ann Endocrinol (Paris) 75(Suppl 1):S21-S36

    Article  Google Scholar 

  2. Bilezikian JP, Brandi ML, Eastell R et al (2014) Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. J Clin Endocrinol 99(10):3561–3569

    Article  CAS  Google Scholar 

  3. Köhler BB, Philippe J (2015) News in endocrinology: Management of asymptomatic primary hyperparathyroidism in 2014. Rev Med Suisse 11(456-457):58–61

    PubMed  Google Scholar 

  4. Marcocci C, Bollerslev J, Khan AA et al (2014) Medical management of primary hyperparathyroidism: proceedings of the Fourth International Workshop of the Management of Asymptomatic Primary Hyperparathyroidism. J Clin Endocrinol Metab 99(10):3607–3185

    Article  CAS  PubMed  Google Scholar 

  5. Singh Ospina N, Thompson GB, Lee RA et al (2015) Safety and efficacy of percutaneous parathyroid ethanol ablation in patients with recurrent primary hyperparathyroidism and multiple endocrine neoplasia type 1. J Clin Endocrinol Metab 100(1):e87-e90

    Article  PubMed  Google Scholar 

  6. National Institutes of Health (1990) Diagnosis and management of asymptomatic primary hyperparathyroidism. NIH Consensus Development Conference. October 29-31, 1990. NIH Consens Statement 8(7): 1–18

    Google Scholar 

  7. Udelsman R, Akerstrom G, Biagini C et al (2014) The surgical management of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop. J Clin Endocrinol Metab 99(10):3595–3606

    Article  CAS  PubMed  Google Scholar 

  8. Bilezikian JP, Khan AA, Potts JT Jr (2009) Third International Workshop on the Management of Asymptomatic Primary Hyperthyroidism. Guidelines for the management of asymptomatic hyperparathyroidism: summary statement from the third international workshop. J Clin Endocrinol Metab 94(2):335–339

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  9. Siverberg SJ, Clarke BL, Peacock M et al (2014) Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop. J Clin Endocrinol Metab 99(10):3580–3594

    Article  Google Scholar 

  10. Agarwal G, Nanda G, Kapoor A et al (2012) Cardiovascular dysfunction in symptomatic primary hyperparathyroidism and its reversal after curative parathyroidectomy: results of a prospective case control study. Surgery 154(6):1394–1403

    Article  Google Scholar 

  11. Pasieka JL (2013) The time has come to redefine the classic symptoms of primary hyperparathyroidism: comment on “parathyroidectomy, elevated depression scores, and suicidal ideation in patients with primary hyperparathyroidism”. JAMA 148(2):115–116

    Google Scholar 

  12. Åberg V, Norenstedt S, Zedenius J et al (2015) Health related quality of life after successful surgery for primary hyperparathyroidectomy: no additive effect from vitamin D supplementation: results of a double-blind randomized study. Eur J Endocrinol 172(2):181–187

    Article  PubMed  Google Scholar 

  13. Brito K, Edirimanne S, Eslick GD (2015) The extent of improvement of health-related quality of life as assessed by the SF36 and Paseika scales after parathyroidectomy in patients with primary hyperparathyroidectomy—a systematic review and meta-analysis. Int J Surg 13:245–249

    Article  PubMed  Google Scholar 

  14. Gopinath P, Sadler GP, Mihai R (2010) Persistent symptomatic improvement in the majority of patients undergoing parathyroidectomy for primary hyperparathyroidism. Langenbecks Arch Surg 395(7):941–946

    Article  PubMed  Google Scholar 

  15. Blanchard C, Mathonnet M, Sebag F et al (2014) Quality of life is modestly improved in older patients with mild primary hyperparathyroidism postoperatively: results of a prospective multicenter study. Ann Surg Oncol 21(11):3534–3540

    Article  PubMed  Google Scholar 

  16. Yeh MW, Wiseman JE, Ituarte PH et al (2012) Surgery for primary hyperparathyroidism: are the consensus guidelines being followed? Ann Surg 255(6):1179–1183

    Article  PubMed  Google Scholar 

  17. Aliabadi-Wahle S, Kelly TL, Rozenfeld Y et al (2014) Treatment strategies for primary hyperparathyroidism: what is the cost? Am Surg 80(11):1146–1151

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Surgical Sciences, University of Turin, Turin, Italy

    Michele Camandona

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  1. Michele Camandona
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Correspondence to Michele Camandona .

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Editors and Affiliations

  1. Department of Surgical Sciences, University of Turin, Turin, Italy

    Guido Gasparri  & Michele Camandona  & 

  2. Department of Surgery, Città della Salute e della Scienza University Hospital, Turin, Italy

    Nicola Palestini

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Camandona, M. (2016). Management of Primary Hyperparathyroidism. In: Gasparri, G., Palestini, N., Camandona, M. (eds) Primary, Secondary and Tertiary Hyperparathyroidism. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-5758-6_8

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  • DOI: https://doi.org/10.1007/978-88-470-5758-6_8

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5757-9

  • Online ISBN: 978-88-470-5758-6

  • eBook Packages: MedicineMedicine (R0)

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