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FDG PET/CT in the Imaging of Mediastinal Masses

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Diseases of the Chest and Heart 2015–2018
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Abstract

Anterior mediastinal tumors that may be encountered on 18F-fluorodeoxyglucose-positron emission tomography/ computed tomography (FDG-PET/CT) scans include malignant lymphoma, benign and malignant germ cell tumors, thymoma, and thymic carcinoma. Of these, lymphomas that involve the mediastinum are the most common.

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References

  1. Dabrowska-Iwanicka A, Walewski JA (2014) Primary mediastinal large B-cell lymphoma. Curr Hematol Malig Rep 9:273–283.

    Article  PubMed Central  PubMed  Google Scholar 

  2. Priola AM, Galetto G, Priola SM (2014) Diagnostic and functional imaging of thymic and mediastinal involvement in lymphoproliferative disorders. Clin Imaging 38:771–784.

    Article  PubMed  Google Scholar 

  3. Weiler-Sagie M, Bushelev O, Epelbaum R et al (2010) F-18-FDG avidity in lymphoma readdressed: a study of 766 patients. J Nucl Med 51:25–30.

    Article  PubMed  Google Scholar 

  4. Schaefer NG, Hany TF, Taverna C et al (2004) Non-Hodgkin lymphoma and Hodgkin disease: coregistered FDG PET and CT at staging and restaging—do we need contrast-enhanced CT? Radiology 232:823–829.

    Article  PubMed  Google Scholar 

  5. Isasi CR, Lu P, Blaufox MD (2005) A metaanalysis of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography in the staging and restaging of patients with lymphoma. Cancer 104:1066–1074.

    Article  PubMed  Google Scholar 

  6. Barrington SF, Mikhaeel NG, Kostakoglu L et al (2014) Role of imaging in the staging and response assessment of lymphoma: consensus of the International conference on Malignant lymphomas imaging working group. J Clin Oncol 32:3048–3058.

    Article  PubMed  Google Scholar 

  7. Cheson BD, Fisher RL, Barrington SF et al (2014) Recommendations for initial evaluation, staging and response assessment of Hodgkin and Non-Hodgkin lymphoma: The Lugano Classification. J Clin Oncol 32:3059–3067.

    Article  PubMed  Google Scholar 

  8. Cheson BD, Pfistner B, Juweid ME et al (2007) Revised response criteria for malignant lymphoma. J Clin Oncol 25:579–586.

    Article  PubMed  Google Scholar 

  9. Biggi A, Gallamini A, Chauvie S et al (2013) International validation study for interim PET in ABVD-treated advancedstage Hodgkin lymphoma: interpretation criteria and concordance rate among reviewers. J Nucl Med 54: 683–690.

    Article  CAS  PubMed  Google Scholar 

  10. Goethals I, Hoste P, Vriendt CD et al (2010) Time-dependent changes in 18F-FDG activity in the thymus and bone marrow following combination chemotherapy in paediatric patients with lymphoma. Eur J Nucl Med Mol Imaging 37:462–467.

    Article  PubMed  Google Scholar 

  11. Gawande RS, Khurana A, Messing S et al (2012) Differentiation of normal thymus from anterior mediastinal lymphoma and lymphoma recurrence at pediatric PET/CT. Radiology 262:613–622.

    Article  PubMed  Google Scholar 

  12. Quint LE (2007) Imaging of anterior mediastinal masses. Cancer Imaging 7:S56–S62.

    Article  PubMed Central  PubMed  Google Scholar 

  13. Lococo F, Cesario A, Okami J et al (2013) Role of combined 18F-FDG-PET/CT for predicting the WHO malignancy grade of thymic epithelial tumors: a multicenter analysis. Lung Cancer 82:245–251.

    Article  CAS  PubMed  Google Scholar 

  14. Luzzi L, Campione A, Gorla A (2009) Role of fluorine-flurodeoxyglucose positron emission tomography/computed tomography in preoperative assessment of anterior mediastinal masses. Eur J Cardiothorac Surg 36:475–479.

    Article  PubMed  Google Scholar 

  15. Treglia G, Sadeghi R, Giovanella L et al (2014) Is 18F-FDG PET useful in predicting the WHO grade of malignancy in thymic epithelial tumors? A metaanalysis. Lung Cancer 86: 5–13.

    Article  PubMed  Google Scholar 

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Khong, PL. (2015). FDG PET/CT in the Imaging of Mediastinal Masses. In: Hodler, J., von Schulthess, G.K., Kubik-Huch, R.A., Zollikofer, C.L. (eds) Diseases of the Chest and Heart 2015–2018. Springer, Milano. https://doi.org/10.1007/978-88-470-5752-4_27

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  • DOI: https://doi.org/10.1007/978-88-470-5752-4_27

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5751-7

  • Online ISBN: 978-88-470-5752-4

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