The Electrocardiogram in Ischemic Heart Disease

  • Massimo Romanò


Reductions in blood flow (and consequently the oxygen supply) to the myocardium can cause transient or permanent damage (ischemia and necrosis, respectively). Atherosclerosis of the coronary arteries is the most common cause. In most cases, the ischemia initially involves the subendocardial layers of the myocardium, which are characterized by a higher metabolic rate and oxygen consumption than the subepicardial layers since they more exposed to extravascular compressive forces (systolic tension, ventricular filling pressure). Only later does the damage extends to the full thickness of the myocardium (Fig. 11.1).


Left Anterior Descend Right Coronary Artery Ischemic Zone Subendocardial Ischemia Subendocardial Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Milan 2015

Authors and Affiliations

  • Massimo Romanò
    • 1
  1. 1.Ospedale Civile di VigevanoVigevanoItaly

Personalised recommendations