Germ Cell Tumor, Ovarian
Ovarian germ cell neoplasms (OGCNs) may be benign or malignant. These neoplasms comprise approximately 20–25 % of ovarian neoplasms overall and arise primarily in young women aged between 10 and 30.
Germ cell tumors are a histologically heterogeneous group of tumors. The main categories of ovarian germ cell tumor are teratomas (the most common benign OGCNs), immature teratomas, dysgerminomas, endodermal sinus or yolk sac tumors, and mixed germ cell tumors. These conditions are bilateral in 10–12 % of cases, while the majority of other histologies present as unilateral ovarian masses. OGCNs often produce hormones, particularly the beta subunit of human chorionic gonadotropin (hCG), and grow rapidly.
Patients typically present with one or more symptoms: abdominal enlargement (from the mass itself, ascites, or both; in 87 % of patients), abdominal pain (from rupture, hemorrhage, or torsion; in 85 % of patients), precocious puberty, abdominal distention, fever,...
KeywordsGerm Cell Tumor Cystic Teratoma Immature Teratoma Mixed Germ Cell Tumor Renal Parenchymal Disease
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