• Valeria Panebianco
  • Jurgen J. Fütterer
Part of the A-Z Notes in Radiological Practice and Reporting book series (AZRPR)

Germ Cell Tumor, Ovarian

  • Ovarian germ cell neoplasms (OGCNs) may be benign or malignant. These neoplasms comprise approximately 20–25 % of ovarian neoplasms overall and arise primarily in young women aged between 10 and 30.

  • Germ cell tumors are a histologically heterogeneous group of tumors. The main categories of ovarian germ cell tumor are teratomas (the most common benign OGCNs), immature teratomas, dysgerminomas, endodermal sinus or yolk sac tumors, and mixed germ cell tumors. These conditions are bilateral in 10–12 % of cases, while the majority of other histologies present as unilateral ovarian masses. OGCNs often produce hormones, particularly the beta subunit of human chorionic gonadotropin (hCG), and grow rapidly.

  • Patients typically present with one or more symptoms: abdominal enlargement (from the mass itself, ascites, or both; in 87 % of patients), abdominal pain (from rupture, hemorrhage, or torsion; in 85 % of patients), precocious puberty, abdominal distention, fever,...


Germ Cell Tumor Cystic Teratoma Immature Teratoma Mixed Germ Cell Tumor Renal Parenchymal Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Zalei Y, Piura B, Elchalal U, et al. 1996. Diagnosis and management of malignant germ cell ovarian tumors in young females. Int J Gynaecol Obstet; 55:1.CrossRefGoogle Scholar
  2. Tewari K, Cappuccini F, Disaia PJ, et al. 2000. Malignant germ cell tumors of the ovary. Obstet Gynecol; 95:128.PubMedGoogle Scholar
  3. Yamaoka T, Togashi K, Koyama T et-al. 2000. Yolk sac tumor of the ovary: radiologic-pathologic correlation in four cases. J Comput Assist Tomogr; 24: 605–9.Google Scholar

Copyright information

© Springer-Verlag Italia 2015

Authors and Affiliations

  • Valeria Panebianco
    • 1
  • Jurgen J. Fütterer
    • 2
    • 3
  1. 1.Department of Radiological Sciences, Oncology and PathologySapienza University of RomeRomeItaly
  2. 2.Department of Radiology and Nuclear MedicineRadboudumcNijmegenThe Netherlands
  3. 3.MIRA Institute for Biomedical Technology and Technical MedicineUniversity of TwenteEnschedeThe Netherlands

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