Multiparametric Magnetic Resonance Imaging in Prostate Cancer Detection

  • Tahir Durmus
  • Alexander Baur
  • Bernd Hamm


Prostate cancer is the most common malignancy in men, but only about 10% of patients die from that cancer. While the incidence rate in the last 30 years has increased fourfold the mortality rate has decreased over the last 20 years [1]. This can be primarily attributed to the early detection of prostate cancer as a result of the common practice of testing the prostate-specific antigen (PSA) in peripheral blood. Trendsetting studies indicate that the current diagnostic and therapeutic approach must be fundamentally rethought. Wilt et al. could not show a significant reduction in mortality rate for patients with a localized tumor who underwent a radical prostatectomy compared with patients who were simply monitored [2]. In addition to possible postoperative complications, radical prostatectomy was associated with a significantly higher morbidity rate (incontinence, erectile dysfunction) [2]. As with radical prostatectomy, radiation therapy is also associated with significant side effects, such as loss of potency, in up to 50% of patients [3].


Prostate Cancer Apparent Diffusion Coefficient Benign Prostate Hyperplasia Radical Prostatectomy Gleason Score 
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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  • Tahir Durmus
    • 1
  • Alexander Baur
    • 1
  • Bernd Hamm
    • 1
  1. 1.Department of Radiology, CharitéUniversitätsmedizin BerlinBerlinGermany

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