Abstract
The end point of any mechanical circulatory support (MCS) is to restore adequacy of perfusion in order to prevent organ damage or to restore normal organ function when damage is already commenced. Reduction of left ventricular end-diastolic pressure, cardiac wall tension, and pulmonary congestion, together with a modulation of the neurohormonal response to acute and chronic heart failure, like endogenous catecholamine, renin-angiotensin system, ANP, and cytokine release, are all aims of mechanical circulatory support.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bartlett RH (2005) Physiology of ECLS. In: Van Meurs K, Lally K, Peek G, Zwischenberger J (eds) ECMO extracorporeal cardiopulmonary support in critical care, 3rd edn. ELSO, Ann Arbor
Marasco SF, Lukas G, McDonald M et al (2008) Review of ECMO (extra corporeal membrane oxygenation) support in critically ill adult patient. Heart Lung Circ 17(Suppl 4):S41–S47
The Hypothermia after Cardiac Arrest Study Group (2002) Mild therapeutic hypothermia to improve the neurologic outcome after cardia arrest. N Engl J Med 346:549–556
Horan M, Ichiba F, Firmin RK et al (2004) A pilot investigation of mild hypothermia in neonates receiving extracorporeal membrane oxygenation (ECMO). J Pediatr 144:301–308
Bavaria JE, Ratcliffe MB, Gupta KB et al (1988) Changes in left ventricular systolic wall stress during biventricular circulatory assistance. Ann Thorac Surg 45:526–532
Hoefer D, Ruttmann E, Poelzl G et al (2006) Outcome evaluation of the bridge to bridge concept in patients with cardiogenic shock. Ann Thorac Surg 82:28–34
Nowlen TT, Salley SO, Whittlesey GC et al (1989) Regional blood flow distribution during extracorporeal membrane oxygenation in rabbits. J Thorac Cardiovasc Surg 98(6):1138–1143
Kato J, Seo T, Ando H et al (1996) Coronary arterial perfusion during venoarterial extracorporeal membrane oxygenation. J Thorac Cardiovasc Surg 111:630–636
Shen I, Levy FH, Vocelka CR et al (2001) Effect of extracorporeal membrane oxygenation on left ventricular function of swine. Ann Thorac Surg 71:862–867
Baldwin JT, Duncan BW (2006) Ventricular assist devices for children. Prog Pediatr Cardiol 21:173–184
Schwarz B, Mair P, Margreiter J et al (2003) Experience with percutaneous venoarterial cardiopulmonary bypass for emergency circulatory support. Crit Care Med 31(3):758–764
Chen YS, Yu HY, Huang SC et al (2005) Experience and result of extracorporeal membrane oxygenation in treating fulminant myocarditis with shock: what mechanical support should be considered first? J Heart Lung Transplant 24:81–87
Doll N, Fabricius A, Borger MA et al (2003) Temporary extracorporeal membrane oxygenation in patients with refractory postoperative cardiogenic shock—a single center experience. J Card Surg 18(6):512–518
Smedira NG, Blackstone EH (2001) Postcardiotomy mechanical support: risk factors and outcomes. Ann Thorac Surg 71(3 Suppl):S60–S66; discussion S82–S85
Murashita T, Eya K, Miyatake T, Kamikubo Y et al (2004) Outcome of the perioperative use of percutaneous cardiopulmonary support for adult cardiac surgery: factors affecting hospital mortality. Artif Organs 28(2):189–195
Pagani FD, Aaronson KD, Dyke DB et al (2000) Assessment of extracorporeal life support to LVAD bridge to heart transplant strategy. Ann Thorac Surg 70:1977–1985
Johnston TA, Jaggers J, McGovern JJ et al (1999) Bedside transseptal balloon dilation atrial septostomy for decompression of the left heart during extracorporeal membrane oxygenation. Catheter Cardiovasc Interv 46(2):197–199
Shibuya M, Kitamura M, Kurihara H et al (1997) Significant left ventricular unloading with transaortic catheter venting during venoarterial bypass. Artif Organs 21(7):789–792
Fumagalli R, Bombino M, Borelli M et al (2004) Percutaneous bridge to heart transplantation by venoarterial ECMO and transaortic left ventricular venting. Int J Artif Organs 27(5):410–413
Scholz KH, Figulla HR, Schröder TT et al (1995) Pulmonary and left ventricular decompression by artificial pulmonary valve incompetence during percutaneous cardiopulmonary bypass support in cardiac arrest. Circulation 91(10):2664–2668
Foti G, Kolobow T, Rossi F et al (1997) Cardiopulmonary bypass through peripheral cannulation with percutaneous decompression of the left heart in a model of severe myocardial failure. ASAIO J 43(6):927–931
Avalli L, Maggioni E, Sangalli F et al (2011) Percutaneous left-heart decompression during extracorporeal membrane oxygenation: an alternative to surgical and transeptal venting in adult patients. ASAIO J 57:38–40
Koeckert MS, Jorde UP, Naka Y et al (2011) Impella LP 2.5 for left ventricular unloading during venoarterial extracorporeal membrane oxygenation support. J Card Surg 26:666–668
Chaparro SV, Badheka A, Marzouka GR et al (2012) Combined use of impella left ventricular assist device and extracorporeal membrane oxygenation as a bridge to recovery in fulminant myocarditis. ASAIO J 58:285–287
Aiyagari RM, Rocchini AP, Remenapp RT et al (2006) Decompression of the left atrium during extracorporeal membrane oxygenation using a transseptal cannula incorporated into the circuit. Crit Care Med 34:2603–2606
Seeto C, Fenn B et al (2000) Ischemic hepatitis: clinical presentation and pathogenesis. AM J Med 1:109–113
Nosae Y (1996) Is it necessary to use metabolic assist for multiorgan failure with left ventricular assist device? No, it should be circulatory assist for splanchnic organs. Artif Organs 20:1
Wigfield CH, Lindsey JD et al (2007) Early institution of extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation improves outcome. J Heart Lung Transplant 26:331–338
Mason DP,MD, Boffa DJ et al (2006) Extended use of extracorporeal membrane oxygenation after lung transplantation. J Thorac Cardiovasc Surg 132:954–960
Rossaint R, Hahn SM, Pappert D et al (1995) Influence of mixed venous PO2 and inspired O2 fraction on intrapulmonary shunt in patients with severe ARDS. J Appl Physiol 78(4):1531–1536
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Italia
About this chapter
Cite this chapter
Mondino, M.G., Milazzo, F., Paino, R., Fumagalli, R. (2014). Extracorporeal Life Support: Interactions with Normal Circulation. In: Sangalli, F., Patroniti, N., Pesenti, A. (eds) ECMO-Extracorporeal Life Support in Adults. Springer, Milano. https://doi.org/10.1007/978-88-470-5427-1_8
Download citation
DOI: https://doi.org/10.1007/978-88-470-5427-1_8
Published:
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-5426-4
Online ISBN: 978-88-470-5427-1
eBook Packages: MedicineMedicine (R0)